Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 2/20 | 0.52 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2924950 | 0.80 | PLAU (0.52) | PLAUNOS3NOS1NOS2NPC1 | |
| SCHEMBL29435535 | 0.80 | PLAU (0.52) | PLAUNOS3NOS1NOS2NPC1 | |
| SCHEMBL1410939 | 0.78 | CYP3A4 (0.47) | PLAUCYP3A4TRPA1NPC1RAB9A | |
| SCHEMBL30520123 | 0.78 | CYP3A4 (0.47) | PLAUCYP3A4TRPA1NPC1RAB9A | |
| SCHEMBL6404182 | 0.77 | — | — | |
| SCHEMBL1851255 | 0.76 | PLAU (0.61) | PLAUNOS3NOS1NOS2NPC1 | |
| SCHEMBL3658777 | 0.76 | TRIM24 (0.34) | PLAUCYP3A4KDM4EGABRA1GABRB2 | |
| SCHEMBL28051639 | 0.76 | TDP1 (0.38) | CYP3A4GABRA1GABRB2HTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11705118 | 0.75 | PLAU (0.55) | PLAUNOS3NOS1NOS2NPC1 | |
| SCHEMBL292776 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220411374-A1 | ALTERNATE PROCESSES FOR THE PREPARATION OF OMECAMTIV MECARBIL | DR. REDDY'S LABORATORIES LIMITED (IN) | 2022-12-29 | — | — | US | disclosed |
| EP-4041710-A1 | ALTERNATE PROCESSES FOR THE PREPARATION OF OMECAMTIV MECARBIL | Dr. Reddy's Laboratories Limited (IN) | 2022-08-17 | — | — | EP | disclosed |
| WO-2021070124-A1 | ALTERNATE PROCESSES FOR THE PREPARATION OF OMECAMTIV MECARBIL | DR. REDDY’S LABORATORIES LIMITED (IN) | 2021-04-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220411374-A1 | ALTERNATE PROCESSES FOR THE PREPARATION OF OMECAMTIV MECARBIL | SI, UMPS, OTC | PLAU 722/4885NOS3 1633/4885NOS1 1199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.