SCHEMBL2321737

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2324653	0.90	FGFR3 (0.41)	MAPTMETALOX5APFEN1PIM1
	SCHEMBL2324685	0.90	PIM1 (0.47)	MAPTMETALOX5APFEN1PIM1
	SCHEMBL2327304	0.87	MET (0.40)	MAPTMETPIM1DYRK1ACLK2
	SCHEMBL2324756	0.87	PIK3CA (0.42)	MAPTMETALOX5APFEN1DYRK1A
	SCHEMBL2325881	0.82	MAPT (0.42)	MAPTMETPIM1DYRK1ACLK2
	SCHEMBL2328465	0.81	MET (0.42)	MAPTMETDYRK1ACLK2MKNK1
	SCHEMBL19791649	0.81	KDR (0.40)	MAPTMETDYRK1ACLK2KDR
	SCHEMBL2327494	0.81	KDR (0.46)	METPIM1DYRK1ACLK2KDR
	SCHEMBL2360342	0.78	TGFBR1 (0.39)	MAPTMETALOX5APFEN1PIM1
	SCHEMBL19791355	0.77	MET (0.42)	METFEN1PIM1TGFBR1PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.