SCHEMBL2328465

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2324653	0.87	FGFR3 (0.41)	METPDPK1DYRK1ACLK2KDR
	SCHEMBL19791649	0.85	KDR (0.40)	METALKPDPK1DYRK1ACLK2
	SCHEMBL2327494	0.85	KDR (0.46)	METALKDYRK1ACLK2CLK1
	SCHEMBL2324756	0.84	PIK3CA (0.42)	METALKDYRK1ACLK2MAPT
	SCHEMBL2325881	0.83	MAPT (0.42)	METDYRK1ACLK2CLK1HIPK1
	SCHEMBL2321737	0.81	MAPT (0.40)	METPDPK1DYRK1ACLK2KDR
	SCHEMBL2324685	0.81	PIM1 (0.47)	METALKPDPK1DYRK1ACLK2
	SCHEMBL2327304	0.78	MET (0.40)	METALKDYRK1ACLK2CSF1R
	SCHEMBL2360342	0.76	TGFBR1 (0.39)	METKDRFGFR3MAPTPFKFB3
	SCHEMBL2364303	0.74	MET (0.41)	METDYRK1AFGFR3GSK3BIRAK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.