SCHEMBL2324653

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2324685	0.90	PIM1 (0.47)	KDRTGFBR1PIM1METMAPT
	SCHEMBL2321737	0.90	MAPT (0.40)	KDRTGFBR1PIM1METMAPT
	SCHEMBL2327304	0.89	MET (0.40)	KDRTGFBR1PIM1METMAPT
	SCHEMBL2360342	0.88	TGFBR1 (0.39)	FGFR3KDRTGFBR1PIM1MET
	SCHEMBL2328465	0.87	MET (0.42)	FGFR3KDRMETMAPTDYRK1A
	SCHEMBL2327513	0.86	MET (0.42)	TGFBR1METFEN1
	SCHEMBL12441209	0.86	MET (0.47)	FGFR3INPPL1METDYRK1AEGFR
	SCHEMBL2321172	0.86	LRRK2 (0.46)	METALOX5APFEN1
	SCHEMBL12440841	0.86	TGFBR1 (0.36)	TGFBR1PIM1METIDO1FEN1
	SCHEMBL12440044	0.86	FEN1 (0.43)	TGFBR1PIM1EGFRFEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.