Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | KCNA2 | P16389 | 2/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CD69 | Q07108 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23217812 | 0.90 | PTGDR2 (0.45) | PTPN1KCNA2KCNA5KCNA1PKM | |
| SCHEMBL23241694 | 0.83 | KDM4E (0.39) | KCNA2KCNA5KCNA1KDM4EKCNA3 | |
| SCHEMBL30010993 | 0.83 | KDM4E (0.39) | KCNA2KCNA5KCNA1KDM4EKCNA3 | |
| SCHEMBL23217709 | 0.81 | PTGDR2 (0.46) | PTPN1KCNA2KCNA5KCNA1PKM | |
| SCHEMBL30010045 | 0.81 | ALDH1A1 (0.41) | KDM4EKCNA3ALDH1A1HSD17B10LMNA | |
| SCHEMBL23217647 | 0.77 | CYP3A4 (0.44) | KCNA2KCNA5KCNA1KDM4EKCNA3 | |
| SCHEMBL23217665 | 0.75 | HTR2A (0.35) | KCNA2KDM4EKCNA3ALDH1A1POLB | |
| SCHEMBL23217258 | 0.74 | KCNA3 (0.38) | KCNA2KCNA5KCNA1KCNA3ALDH1A1 | |
| SCHEMBL23241702 | 0.73 | KDM4E (0.39) | KCNA2KCNA5KCNA1KDM4EKCNA3 | |
| SCHEMBL30009732 | 0.73 | KDM4E (0.39) | KCNA2KCNA5KCNA1KDM4EKCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021072156-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |