Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.37 |
| ▸ | KCNA2 | P16389 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23217654 | 0.83 | ALDH1A1 (0.38) | TSHRKCNA2KCNA5KCNA1KCNA3 | |
| SCHEMBL23217206 | 0.82 | PTPN1 (0.37) | POLBPTPN1KCNA2KCNA5KCNA1 | |
| SCHEMBL23217508 | 0.81 | PTPN1 (0.38) | PTGDR2TSHRPOLBPTPN1KCNA2 | |
| SCHEMBL23217812 | 0.81 | PTGDR2 (0.45) | PTGDR2TSHRPOLBPTPN1KCNA2 | |
| SCHEMBL29481725 | 0.79 | ALDH1A1 (0.36) | TSHRTDP1PTPN1KCNA2PKM | |
| SCHEMBL19775924 | 0.79 | ALDH1A1 (0.36) | TSHRTDP1PTPN1KCNA2PKM | |
| SCHEMBL21468873 | 0.79 | ALDH1A1 (0.36) | TSHRTDP1PTPN1KCNA2PKM | |
| SCHEMBL23217746 | 0.78 | NLRP3 (0.43) | POLBPTPN1KCNA3ALOX15ALDH1A1 | |
| SCHEMBL23217471 | 0.77 | KCNA2 (0.39) | KCNA2KCNA5KCNA1KCNA3KMT2A | |
| SCHEMBL23217221 | 0.75 | PTPN1 (0.38) | POLBPTPN1KCNA2KCNA3ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021072156-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |