Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KCNA2 | P16389 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | PTPRF | P10586 | 1/20 | 0.35 |
| ▸ | PTPRA | P18433 | 1/20 | 0.35 |
| ▸ | PTPRB | P23467 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23217508 | 0.90 | PTPN1 (0.38) | PTGDR2ALOX15TSHRHSD17B10KDM4E | |
| SCHEMBL23241702 | 0.83 | KDM4E (0.39) | TSHRHSD17B10MAPTKDM4EALDH1A1 | |
| SCHEMBL30009732 | 0.83 | KDM4E (0.39) | TSHRHSD17B10MAPTKDM4EALDH1A1 | |
| SCHEMBL23217660 | 0.81 | KCNA3 (0.36) | ALOX15MAPTKDM4EALDH1A1POLB | |
| SCHEMBL23217709 | 0.81 | PTGDR2 (0.46) | PTGDR2ALOX15TSHRHSD17B10KDM4E | |
| SCHEMBL30010435 | 0.81 | ALDH1A1 (0.41) | HSD17B10KDM4EALDH1A1LMNAKCNA3 | |
| SCHEMBL23217831 | 0.79 | CYP3A4 (0.43) | ALOX15MAPTKDM4EALDH1A1POLB | |
| SCHEMBL23217270 | 0.76 | KCNA2 (0.40) | HSD17B10KCNA2KCNA5KCNA1KCNA3 | |
| SCHEMBL23217816 | 0.76 | HTR2A (0.34) | ALOX15KDM4EALDH1A1POLBKCNA2 | |
| SCHEMBL23241694 | 0.73 | KDM4E (0.39) | TSHRHSD17B10MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021072156-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |