Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.35 |
| ▸ | CYP3A43 | Q9HB55 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KCNA3 | P22001 | 6/20 | 0.33 |
| ▸ | KCNA2 | P16389 | 3/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23241702 | 1.00 | KDM4E (0.39) | KDM4EHPGDALDH1A1HSD17B10MEN1 | |
| SCHEMBL23241694 | 0.91 | KDM4E (0.39) | KDM4EHPGDALDH1A1HSD17B10MEN1 | |
| SCHEMBL30010993 | 0.91 | KDM4E (0.39) | KDM4EHPGDALDH1A1HSD17B10MEN1 | |
| SCHEMBL23217654 | 0.83 | ALDH1A1 (0.38) | KDM4EHPGDALDH1A1HSD17B10MEN1 | |
| SCHEMBL23217812 | 0.83 | PTGDR2 (0.45) | KDM4EALDH1A1HSD17B10TSHRMAPT | |
| SCHEMBL30010435 | 0.81 | ALDH1A1 (0.41) | KDM4EALDH1A1HSD17B10LMNAKCNA3 | |
| SCHEMBL30009863 | 0.79 | L3MBTL1 (0.37) | KDM4EHPGDALDH1A1HSD17B10MEN1 | |
| SCHEMBL23241696 | 0.79 | L3MBTL1 (0.37) | KDM4EHPGDALDH1A1HSD17B10MEN1 | |
| SCHEMBL23217660 | 0.78 | KCNA3 (0.36) | KDM4EHPGDALDH1A1CYP2C19CYP1A1 | |
| SCHEMBL23217831 | 0.76 | CYP3A4 (0.43) | KDM4EHPGDALDH1A1CYP2C19CYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250275991-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2025-09-04 | — | — | US | disclosed |
| EP-4041717-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-08-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250275991-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | CFD, CFH, CFB | KDM4E 4182/4885HPGD 336/4885ALDH1A1 3388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.