Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CPA3 | P15088 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.40 |
| ▸ | EEF2K | O00418 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 2/20 | 0.38 |
| ▸ | GABRD | O14764 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31084151 | 0.84 | CNR2 (0.46) | GAACNR2ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL7236109 | 0.82 | EEF2K (0.47) | GAACNR2CES2CES1MEN1 | |
| SCHEMBL3511352 | 0.82 | EEF2K (0.47) | GAACNR2CES2CES1MEN1 | |
| SCHEMBL2457680 | 0.82 | EEF2K (0.47) | GAACNR2CES2CES1MEN1 | |
| SCHEMBL11495829 | 0.81 | CES2 (0.46) | GAACNR2ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL21632058 | 0.80 | GABBR2 (0.45) | GAACNR2ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL27538066 | 0.79 | MMP2 (0.46) | GAACNR2ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL811540 | 0.79 | CYP2D6 (0.42) | ALDH1A1CYP1A2CYP2D6TSHRCYP2C19 | |
| SCHEMBL11085997 | 0.79 | GAA (0.47) | GAACNR2ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL27728236 | 0.79 | CPA3 (0.45) | GAACNR2ALDH1A1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021072167-A1 | COMPOSITIONS AND METHODS FOR IN VIVO SYNTHESIS OF UNNATURAL POLYPEPTIDES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-04-15 | — | — | WO | disclosed |