Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 9/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23217676 | 0.90 | L3MBTL1 (0.35) | CFDTBXAS1KDM4EALDH1A1MAPT | |
| SCHEMBL30010562 | 0.89 | TBXAS1 (0.33) | CFDTBXAS1KDM4EALDH1A1MAPT | |
| SCHEMBL30010940 | 0.87 | TBXAS1 (0.38) | CFDTBXAS1KDM4EALDH1A1MAPT | |
| SCHEMBL23217611 | 0.87 | TBXAS1 (0.38) | CFDTBXAS1KDM4EALDH1A1MAPT | |
| SCHEMBL23217708 | 0.86 | HPGD (0.40) | CFDTBXAS1KDM4EALDH1A1MAPT | |
| SCHEMBL29672991 | 0.86 | HPGD (0.40) | CFDTBXAS1KDM4EALDH1A1MAPT | |
| SCHEMBL23217579 | 0.84 | CFD (0.51) | CFD | |
| Hexane SCHEMBL23217870 | 0.83 | HPGD (0.38) | CFDTBXAS1KDM4EALDH1A1MAPT | |
| SCHEMBL23217589 | 0.79 | CFD (0.46) | CFD | |
| SCHEMBL21438395 | 0.77 | CFD (0.52) | CFDTBXAS1PKMPRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114555570-A | Oral complement factor D inhibitors | 拜奥克里斯特制药公司 | 2022-05-27 | — | — | CN | disclosed |
| WO-2021072156-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |