Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | CFD | P00746 | 5/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29672991 | 0.96 | HPGD (0.40) | HPGDKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL23217708 | 0.96 | HPGD (0.40) | HPGDKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL30010940 | 0.86 | TBXAS1 (0.38) | HPGDKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL23217611 | 0.86 | TBXAS1 (0.38) | HPGDKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL30010562 | 0.84 | TBXAS1 (0.33) | HPGDKDM4EALDH1A1MAPTNR4A1 | |
| SCHEMBL23217814 | 0.83 | CFD (0.36) | HPGDKDM4EALDH1A1MAPTTBXAS1 | |
| SCHEMBL23217277 | 0.80 | CFD (0.49) | HPGDKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL23217676 | 0.80 | L3MBTL1 (0.35) | HPGDKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL21438395 | 0.76 | CFD (0.52) | TBXAS1CFDPKM | |
| SCHEMBL30010728 | 0.76 | CFD (0.52) | TBXAS1CFDPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021072156-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |