Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21437650 | 0.87 | HTR2A (0.33) | HTR2C | |
| SCHEMBL23219171 | 0.82 | HTR2A (0.33) | HTR2C | |
| SCHEMBL23218438 | 0.77 | PTPN1 (0.31) | — | |
| SCHEMBL24199941 | 0.76 | KCNA2 (0.30) | — | |
| SCHEMBL4992632 | 0.74 | GYS1 (0.30) | HTR2C | |
| SCHEMBL26475950 | 0.73 | PTPN1 (0.34) | — | |
| SCHEMBL23218572 | 0.71 | NPC1 (0.32) | HTR2C | |
| SCHEMBL6305380 | 0.71 | HTR2A (0.32) | HTR2C | |
| SCHEMBL21438255 | 0.71 | HTR2A (0.33) | HTR2C | |
| SCHEMBL16855179 | 0.70 | DRD2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041238-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-08-17 | — | — | EP | disclosed |
| WO-2021072198-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |