Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.36 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.34 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.34 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TSPO | P30536 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23219249 | 0.78 | KDM4E (0.39) | PDE4BKMT2AMEN1KDM4ENPC1 | |
| SCHEMBL23218320 | 0.76 | NLRP3 (0.42) | PDE4BDNMT1ELANENLRP3 | |
| SCHEMBL23219154 | 0.76 | CFD (0.40) | KMT2AMEN1KDM4EELANENLRP3 | |
| SCHEMBL15970798 | 0.70 | MAPK8 (0.40) | PDE4BKMT2AMEN1NPC1RAB9A | |
| SCHEMBL23467048 | 0.69 | NLRP3 (0.40) | PDE4BKMT2AMEN1TSPOELANE | |
| SCHEMBL17195540 | 0.68 | NLRP3 (0.43) | PDE4BKMT2AMEN1ELANENLRP3 | |
| SCHEMBL13322762 | 0.68 | PDGFRA (0.44) | PDE4BKMT2AMEN1NLRP3 | |
| SCHEMBL23219224 | 0.68 | LMNA (0.37) | PDE4BKMT2AELANENLRP3TSHR | |
| SCHEMBL23218912 | 0.67 | ELANE (0.45) | KMT2AHTR4ELANENLRP3 | |
| SCHEMBL20740627 | 0.67 | ELANE (0.42) | HTR4BAZ2BELANENLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021072198-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |