SCHEMBL23219506

SCHEMBL23219506

CC(C)(C)c1ccc(/N=C/c2ccccc2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 6/20 0.66
CA2 P00918 6/20 0.66
PTGS2 P35354 4/20 0.50
CA12 O43570 1/20 0.50
CA9 Q16790 1/20 0.50
L3MBTL1 Q9Y468 3/20 0.49
KDM4E B2RXH2 2/20 0.49
ALDH1A1 P00352 2/20 0.49
GLA P06280 1/20 0.49
ESRRG P62508 1/20 0.47
MAPT P10636 2/20 0.44
MEN1 O00255 1/20 0.44
TP53 P04637 1/20 0.44
THRB P10828 1/20 0.44
ALOX15 P16050 1/20 0.44
MAPK1 P28482 1/20 0.44
KMT2A Q03164 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
HSD17B10 Q99714 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23219507 0.92 CA1 (0.66) CA1CA2PTGS2CA12CA9
SCHEMBL11813972 0.89 CA2 (0.53) CA1CA2PTGS2CA12CA9
SCHEMBL11813969 0.89 CA2 (0.53) CA1CA2PTGS2CA12CA9
SCHEMBL3417678 0.83 CA2 (0.69) CA1CA2PTGS2CA12CA9
SCHEMBL3417682 0.83 CA2 (0.69) CA1CA2PTGS2CA12CA9
SCHEMBL27622892 0.83 CA2 (0.64) CA1CA2PTGS2CA12CA9
SCHEMBL29205583 0.81 CA1 (0.62) CA1CA2PTGS2CA12CA9
SCHEMBL13580880 0.81 CA2 (0.62) CA1CA2PTGS2CA9L3MBTL1
SCHEMBL7870682 0.81 PTGS2 (0.59) CA1CA2PTGS2CA12CA9
SCHEMBL28964163 0.80 DHODH (0.65) CA1CA2L3MBTL1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10975307-B2 Liquid crystalline epoxy compound with terminal mesogen connected by flexible linkage and method for preparing the same KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2021-04-13 US disclosed