Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGF1 | P05230 | 1/20 | 0.35 |
| ▸ | CD209 | Q9NNX6 | 1/20 | 0.32 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.31 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.31 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.31 |
| ▸ | SELL | P14151 | 2/20 | 0.31 |
| ▸ | SELP | P16109 | 1/20 | 0.31 |
| ▸ | GJB2 | P29033 | 1/20 | 0.31 |
| ▸ | IGF2R | P11717 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18936351 | 1.00 | FGF1 (0.35) | FGF1CD209LGALS8LGALS3LGALS4 | |
| SCHEMBL23028969 | 0.92 | GJB2 (0.34) | FGF1CD209LGALS8LGALS3LGALS4 | |
| SCHEMBL20988377 | 0.92 | FGF1 (0.34) | FGF1CD209LGALS8LGALS3LGALS4 | |
| SCHEMBL19797817 | 0.89 | FGF1 (0.33) | FGF1CD209LGALS8LGALS3LGALS4 | |
| SCHEMBL20216523 | 0.87 | FGF1 (0.38) | FGF1CD209LGALS8LGALS3LGALS4 | |
| SCHEMBL24495906 | 0.83 | LGALS3 (0.39) | FGF1LGALS8LGALS3LGALS4SELL | |
| SCHEMBL22200274 | 0.82 | FGF1 (0.38) | FGF1CD209LGALS8LGALS3LGALS4 | |
| SCHEMBL21908695 | 0.81 | ALDH1A1 (0.37) | FGF1LGALS8LGALS3LGALS4SELL | |
| SCHEMBL19325097 | 0.81 | MAPK1 (0.37) | FGF1LGALS8LGALS3LGALS4SELL | |
| SCHEMBL21908706 | 0.79 | LGALS3 (0.41) | FGF1LGALS8LGALS3LGALS4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10976324-B2 | Synergistic combination of biomarkers for detecting and assessing hepatic fibrosis | UNIVERSITÉ PARIS CITÉ (FR) | 2021-04-13 | — | — | US | disclosed |