Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.38 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.38 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18051394 | 0.84 | TERT (0.42) | TERTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL27972544 | 0.83 | MEN1 (0.56) | SMN1; SMN2TERTMEN1KMT2AALDH1A1 | |
| SCHEMBL1359228 | 0.82 | MEN1 (0.60) | SMN1; SMN2TERTMEN1KMT2AALDH1A1 | |
| SCHEMBL28079062 | 0.82 | TERT (0.48) | SMN1; SMN2TERTALDH1A1MAPTKDM4E | |
| SCHEMBL805864 | 0.81 | MAPT (0.64) | HSD11B1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL30598256 | 0.81 | TERT (0.49) | SMN1; SMN2HSD11B1TERTMEN1KMT2A | |
| SCHEMBL1914634 | 0.81 | TERT (0.49) | SMN1; SMN2TERTMEN1KMT2AALDH1A1 | |
| SCHEMBL3499447 | 0.81 | TERT (0.49) | SMN1; SMN2HSD11B1TERTMEN1KMT2A | |
| SCHEMBL30598255 | 0.81 | TERT (0.49) | SMN1; SMN2TERTMEN1KMT2AALDH1A1 | |
| SCHEMBL348592 | 0.81 | ALDH1A1 (0.44) | TERTALDH1A1MAPTHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |