Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 7/20 | 0.49 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CTRC | Q99895 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30598256 | 1.00 | TERT (0.49) | TERTCNR2CNR1KMOHSD11B1 | |
| SCHEMBL27972544 | 0.83 | MEN1 (0.56) | TERTALDH1A1RAB9AKDM4ENPC1 | |
| SCHEMBL1359228 | 0.82 | MEN1 (0.60) | TERTCNR1ALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL1914634 | 0.81 | TERT (0.49) | TERTALDH1A1RAB9AKDM4ENPC1 | |
| SCHEMBL30598255 | 0.81 | TERT (0.49) | TERTALDH1A1RAB9AKDM4ENPC1 | |
| SCHEMBL2321964 | 0.81 | SMN1; SMN2 (0.41) | TERTHSD11B1ALDH1A1RAB9AKDM4E | |
| SCHEMBL805864 | 0.81 | MAPT (0.64) | HSD11B1ALDH1A1RAB9ANPC1HSD17B10 | |
| SCHEMBL5981465 | 0.81 | TERT (0.49) | TERTKMOALDH1A1RAB9AKDM4E | |
| SCHEMBL12539129 | 0.80 | HSD17B14 (0.51) | TERTCNR2CNR1KMO | |
| SCHEMBL29476108 | 0.80 | CCR1 (0.48) | TERTALDH1A1RAB9AKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110511253-B | Synthesis method of On-DNA tetrahydro-beta-carboline compound in construction of DNA coding compound library | 上海药明康德新药开发有限公司 | 2023-10-13 | — | — | CN | claimed |
| US-20100130737-A1 | Regulating Agent of GPR34 Receptor Function | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-05-27 | — | — | US | disclosed |
| EP-1849465-A1 | AGENT FOR CONTROLLING FUNCTION OF GPR34 RECEPTOR | Takeda Pharmaceutical Company Limited (JP) | 2007-10-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130737-A1 | Regulating Agent of GPR34 Receptor Function | GPR34, GPR4, GPR6 | TERT 4584/4885CNR2 63/4885CNR1 44/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.