Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 1/20 | 0.48 |
| ▸ | KMO | O15229 | 2/20 | 0.48 |
| ▸ | XDH | P47989 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.41 |
| ▸ | SDHB | P21912 | 1/20 | 0.40 |
| ▸ | ATP4A | P20648 | 2/20 | 0.39 |
| ▸ | ATP4B | P51164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18051394 | 0.88 | TERT (0.42) | TERTKMOXDHRAB9AACHE | |
| SCHEMBL2321964 | 0.82 | SMN1; SMN2 (0.41) | TERTRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL5981646 | 0.81 | NPC1 (0.44) | TERTRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL3629467 | 0.81 | IDO1 (0.55) | KMOXDHIDO1METAP2RAB9A | |
| SCHEMBL12538541 | 0.80 | TRPV3 (0.45) | TERTXDHRAB9AACHEALDH1A1 | |
| SCHEMBL1359228 | 0.80 | MEN1 (0.60) | TERTRAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL4401764 | 0.79 | IDO1 (0.53) | KMOXDHIDO1METAP2RAB9A | |
| SCHEMBL27972260 | 0.79 | HSD17B14 (0.46) | RAB9ANPC1KDM4EALDH1A1MAPT | |
| SCHEMBL16179917 | 0.79 | ALDH1A1 (0.59) | TERTRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL2320110 | 0.78 | KMO (0.48) | TERTKMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103923105-B | 2-indolizine Carbox amide and preparation thereof and purposes | 北京大学 | 2016-08-24 | — | — | CN | disclosed |