Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV6 | Q9H1D0 | 5/20 | 0.79 |
| ▸ | ORAI1 | Q96D31 | 4/20 | 0.79 |
| ▸ | ORAI2 | Q96SN7 | 4/20 | 0.79 |
| ▸ | ORAI3 | Q9BRQ5 | 4/20 | 0.79 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | MGLL | Q99685 | 3/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.54 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CTRC | Q99895 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Boric Acid SCHEMBL29051220 | 0.86 | CYP1A2 (0.79) | TRPV6ORAI1ORAI2ORAI3CYP1A2 | |
| SCHEMBL2407457 | 0.86 | TRPV6 (0.74) | TRPV6ORAI1ORAI2ORAI3CYP1A2 | |
| SCHEMBL1138482 | 0.83 | TRPV6 (0.80) | TRPV6ORAI1ORAI2ORAI3CA1 | |
| SCHEMBL4454036 | 0.81 | CYP1A2 (1.00) | CYP1A2KDM4ELMNAGAAL3MBTL1 | |
| SCHEMBL183912 | 0.81 | CYP1A2 (1.00) | CYP1A2KDM4ELMNAGAAL3MBTL1 | |
| SCHEMBL23219856 | 0.78 | TRPV6 (0.70) | TRPV6ORAI1ORAI2ORAI3MGLL | |
| Water SCHEMBL6336149 | 0.78 | CYP1A2 (0.94) | CYP1A2KDM4ELMNAGAAL3MBTL1 | |
| Water SCHEMBL10875875 | 0.78 | CYP1A2 (0.94) | CYP1A2KDM4ELMNAGAAL3MBTL1 | |
| Hydrogen Sulfide SCHEMBL7195075 | 0.78 | CYP1A2 (0.94) | CYP1A2KDM4ELMNAGAAL3MBTL1 | |
| Phosphine SCHEMBL5144006 | 0.78 | CYP1A2 (0.94) | CYP1A2KDM4ELMNAGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10973835-B2 | Boron-containing small molecules for inhibiting activity of a receptor-like protein tyrosine phosphatase | THE PENN STATE RESEARCH FOUNDATION (US) | 2021-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10973835-B2 | Boron-containing small molecules for inhibiting activity of a receptor-like protein tyrosine phosphatase | PTPRO, PTPRR, PPP1R1B | TRPV6 1500/4885ORAI1 3960/4885ORAI2 3409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.