Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV6 | Q9H1D0 | 6/20 | 0.80 |
| ▸ | ORAI1 | Q96D31 | 5/20 | 0.80 |
| ▸ | ORAI2 | Q96SN7 | 5/20 | 0.80 |
| ▸ | ORAI3 | Q9BRQ5 | 5/20 | 0.80 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4833078 | 0.87 | TRPV6 (0.76) | TRPV6ORAI1ORAI2ORAI3ENPP2 | |
| SCHEMBL23219857 | 0.83 | TRPV6 (0.79) | TRPV6ORAI1ORAI2ORAI3ENPP2 | |
| SCHEMBL1138541 | 0.82 | ORAI1 (0.57) | TRPV6ORAI1ORAI2ORAI3ENPP2 | |
| SCHEMBL28166 | 0.81 | ENPP2 (1.00) | TRPV6ORAI1ORAI2ORAI3ENPP2 | |
| SCHEMBL19712647 | 0.80 | ENPP2 (0.59) | TRPV6ORAI1ORAI2ORAI3ENPP2 | |
| SCHEMBL28117303 | 0.79 | ENPP2 (0.94) | TRPV6ORAI1ORAI2ORAI3ENPP2 | |
| SCHEMBL27648777 | 0.79 | ENPP2 (0.94) | TRPV6ORAI1ORAI2ORAI3ENPP2 | |
| SCHEMBL4827542 | 0.77 | TRPV6 (0.62) | TRPV6ORAI1ORAI2ORAI3ENPP2 | |
| SCHEMBL17655876 | 0.77 | ENPP2 (0.62) | TRPV6ORAI1ORAI2ORAI3ENPP2 | |
| SCHEMBL1138563 | 0.77 | ENPP2 (0.62) | TRPV6ORAI1ORAI2ORAI3ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230340530-A1 | Methods of Protecting RNA | PFIZER INC. (US) | 2023-10-26 | — | — | US | claimed |
| EP-4204012-A1 | METHODS OF PROTECTING RNA | Pfizer Inc. (US) | 2023-07-05 | — | — | EP | claimed |
| US-9868694-B2 | Process for preparing chlorinated biphenylanilides and biphenylanilines | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-01-16 | — | — | US | claimed |
| EP-1856024-B2 | METHOD FOR PRODUCING SUBSTITUTED BIPHENYLS | BASF SE (DE) | 2011-08-17 | — | — | EP | claimed |
| US-7772446-B2 | Method for producing substituted biphenyls | BASF SE (DE) | 2010-08-10 | — | — | US | claimed |
| US-20090082561-A1 | Methods For The Preparation Of Alkyl Diaryl Borinates And Complexed Diarylboronic Acids | THE PENNSYLVANIA STATE RESEARCH FOUNDATION | 2009-03-26 | — | — | US | claimed |
| EP-1856024-B1 | METHOD FOR PRODUCING SUBSTITUTED BIPHENYLS | BASF SE (DE) | 2008-08-06 | — | — | EP | claimed |
| US-20080183021-A1 | Method for Producing Substituted Biphenyls | BASF SE (DE) | 2008-07-31 | — | — | US | claimed |
| EP-1856024-A1 | METHOD FOR PRODUCING SUBSTITUTED BIPHENYLS | BASF AKTIENGESELLSCHAFT (DE) | 2007-11-21 | — | — | EP | claimed |
| WO-2006092429-A1 | METHOD FOR PRODUCING SUBSTITUTED BIPHENYLS | BASF AKTIENGESELLSCAHFT (DE) | 2006-09-08 | — | — | WO | claimed |
| US-20050080048-A1 | Methods for the preparation of alkyl diaryl borinates and complexed diarylboronic acids | PENN STATE RESEARCH FOUNDATION, THE | 2005-04-14 | — | — | US | claimed |
| EP-1463739-A2 | METHODS FOR THE PREPARATION OF ALKYL DIARYL BORINATES AND COMPLEXED DIARYLBORINIC ACIDS | THE PENNSYLVANIA STATE RESEARCH FOUNDATION (US) | 2004-10-06 | — | — | EP | claimed |
| US-6600066-B1 | Process for preparing perhalogenated monoorganoboranes or diorganoboranes which makes it possible to obtain these compounds under conditions which can readily be implemented in the industry is described. | BASELL POLYOLEFINE GMBH (DE) | 2003-07-29 | — | — | US | claimed |
| WO-2003059916-A2 | METHODS FOR THE PREPARATION OF ALKYL DIARYL BORINATES AND COMPLEXED DIARYLBORINIC ACIDS | THE PENNSYLVANIA STATE RESEARCH FOUNDATION (US) | 2003-07-24 | — | — | WO | claimed |
| EP-1140947-B1 | METHOD FOR PRODUCING MONO-ORGANOBORANES OR DI-ORGANOBORANES | BASELL POLYOLEFINE GMBH (DE) | 2003-03-12 | — | — | EP | claimed |
| EP-1140947-A1 | METHOD FOR PRODUCING MONO-ORGANOBORANES OR DI-ORGANOBORANES | Basell Polyolefine GmbH (DE) | 2001-10-10 | — | — | EP | claimed |
| WO-2000037476-A1 | METHOD FOR PRODUCING MONO-ORGANOBORANES OR DI-ORGANOBORANES | BASELL POLYOLEFINE GMBH (DE) | 2000-06-29 | — | — | WO | claimed |
| US-20230340530-A1 | Methods of Protecting RNA | PFIZER INC. (US) | 2023-10-26 | — | — | US | disclosed |
| EP-1003753-A1 | COMPOUNDS CONTAINING BORON AND ALUMINIUM | Basell Polyolefine GmbH (DE) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999006414-A1 | COMPOUNDS CONTAINING BORON AND ALUMINIUM | TARGOR GMBH (DE) | 1999-02-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090082561-A1 | Methods For The Preparation Of Alkyl Diaryl Borinates And Complexed Diarylboronic Acids | BCL6B, BLVRB, SSB | TRPV6 1769/4885ORAI1 1065/4885ORAI2 874/4885 |
| US-20050080048-A1 | Methods for the preparation of alkyl diaryl borinates and complexed diarylboronic acids | BCL6B, BLVRB, SSB | TRPV6 1769/4885ORAI1 1065/4885ORAI2 874/4885 |
| US-20080183021-A1 | Method for Producing Substituted Biphenyls | CBR3, DDT, HRH3 | TRPV6 1463/4885ORAI1 4349/4885ORAI2 4364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.