Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV6 | Q9H1D0 | 6/20 | 0.70 |
| ▸ | ORAI1 | Q96D31 | 5/20 | 0.70 |
| ▸ | ORAI2 | Q96SN7 | 5/20 | 0.70 |
| ▸ | ORAI3 | Q9BRQ5 | 5/20 | 0.70 |
| ▸ | MGLL | Q99685 | 3/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.54 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.43 |
| ▸ | BAD | Q92934 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2407457 | 0.86 | TRPV6 (0.74) | TRPV6ORAI1ORAI2ORAI3MGLL | |
| Boric Acid SCHEMBL6658261 | 0.86 | MGLL (0.54) | TRPV6ORAI1ORAI2ORAI3MGLL | |
| Boric Acid SCHEMBL28048955 | 0.86 | MGLL (0.54) | TRPV6ORAI1ORAI2ORAI3MGLL | |
| SCHEMBL1003006 | 0.83 | TRPV6 (1.00) | TRPV6ORAI1ORAI2ORAI3MGLL | |
| SCHEMBL12444110 | 0.81 | ALDH1A1 (0.60) | BCL2L1BADMEN1POLBKMT2A | |
| SCHEMBL412237 | 0.81 | ALDH1A1 (0.60) | BCL2L1BADMEN1POLBKMT2A | |
| SCHEMBL7938359 | 0.81 | ALDH1A1 (0.60) | BCL2L1BADMEN1POLBKMT2A | |
| SCHEMBL23219879 | 0.80 | CA1 (0.48) | TRPV6ORAI1ORAI2ORAI3MGLL | |
| SCHEMBL23219857 | 0.78 | TRPV6 (0.79) | TRPV6ORAI1ORAI2ORAI3MGLL | |
| Water SCHEMBL6337149 | 0.78 | ALDH1A1 (0.56) | BCL2L1BADMEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10973835-B2 | Boron-containing small molecules for inhibiting activity of a receptor-like protein tyrosine phosphatase | THE PENN STATE RESEARCH FOUNDATION (US) | 2021-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10973835-B2 | Boron-containing small molecules for inhibiting activity of a receptor-like protein tyrosine phosphatase | PTPRO, PTPRR, PPP1R1B | TRPV6 1500/4885ORAI1 3960/4885ORAI2 3409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.