Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.44 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.44 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.44 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17236459 | 0.81 | ENPP2 (0.52) | ENPP2LMNACYP2A6ORAI1ORAI2 | |
| SCHEMBL1017379 | 0.73 | ENPP2 (0.58) | ENPP2LMNACYP2A6ORAI1ORAI2 | |
| SCHEMBL7673010 | 0.71 | ENPP2 (0.55) | ENPP2LMNACYP2A6ORAI1ORAI2 | |
| SCHEMBL17868174 | 0.71 | ORAI1 (0.55) | ORAI1ORAI2ORAI3TRPV6IDO1 | |
| 1,4-Dichlorobenzene SCHEMBL11243685 | 0.71 | — | — | |
| 1,4-Dichlorobenzene SCHEMBL5191 | 0.71 | — | — | |
| SCHEMBL28166 | 0.69 | ENPP2 (1.00) | ENPP2LMNACYP2A6ORAI1ORAI2 | |
| SCHEMBL1138482 | 0.69 | TRPV6 (0.80) | ENPP2LMNACYP2A6ORAI1ORAI2 | |
| SCHEMBL14309780 | 0.69 | ENPP2 (0.52) | ENPP2LMNACYP2A6ORAI1ORAI2 | |
| SCHEMBL1032443 | 0.67 | TRPV6 (0.47) | ENPP2LMNAORAI1ORAI2ORAI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10973835-B2 | Boron-containing small molecules for inhibiting activity of a receptor-like protein tyrosine phosphatase | THE PENN STATE RESEARCH FOUNDATION (US) | 2021-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10973835-B2 | Boron-containing small molecules for inhibiting activity of a receptor-like protein tyrosine phosphatase | PTPRO, PTPRR, PPP1R1B | ENPP2 404/4885LMNA 4860/4885CYP2A6 328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.