Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.55 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.55 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.55 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23219879 | 0.83 | CA1 (0.48) | ORAI1ORAI2ORAI3TRPV6CA1 | |
| SCHEMBL17236450 | 0.80 | ORAI1 (0.55) | ORAI1ORAI2ORAI3TRPV6CA1 | |
| SCHEMBL125724 | 0.76 | ORAI1 (0.58) | ORAI1ORAI2ORAI3TRPV6CA1 | |
| SCHEMBL13499 | 0.73 | — | — | |
| SCHEMBL5508 | 0.71 | ORAI1 (0.68) | ORAI1ORAI2ORAI3TRPV6CA1 | |
| SCHEMBL21979751 | 0.71 | ORAI1 (0.68) | ORAI1ORAI2ORAI3TRPV6CA1 | |
| SCHEMBL16978178 | 0.71 | ORAI1 (0.52) | ORAI1ORAI2ORAI3TRPV6CA1 | |
| SCHEMBL1003006 | 0.71 | TRPV6 (1.00) | ORAI1ORAI2ORAI3TRPV6CA1 | |
| SCHEMBL23219881 | 0.71 | ENPP2 (0.52) | ORAI1ORAI2ORAI3TRPV6CA1 | |
| SCHEMBL1032443 | 0.69 | TRPV6 (0.47) | ORAI1ORAI2ORAI3TRPV6CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10973835-B2 | Boron-containing small molecules for inhibiting activity of a receptor-like protein tyrosine phosphatase | THE PENN STATE RESEARCH FOUNDATION (US) | 2021-04-13 | — | — | US | disclosed |
| US-9991452-B2 | Condensed-cyclic compound and organic light-emitting device including the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2018-06-05 | — | — | US | disclosed |
| US-9991452-B2 | Condensed-cyclic compound and organic light-emitting device including the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2018-06-05 | — | — | US | disclosed |
| US-9991452-B2 | Condensed-cyclic compound and organic light-emitting device including the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2018-06-05 | — | — | US | disclosed |
| US-20160190448-A1 | CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2016-06-30 | — | — | US | disclosed |
| US-20160190448-A1 | CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2016-06-30 | — | — | US | disclosed |
| US-20160190448-A1 | CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2016-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10973835-B2 | Boron-containing small molecules for inhibiting activity of a receptor-like protein tyrosine phosphatase | PTPRO, PTPRR, PPP1R1B | ORAI1 3960/4885ORAI2 3409/4885ORAI3 4172/4885 |
| US-20160190448-A1 | CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | CCNT1, CCNE2, CRY1 | ORAI1 2987/4885ORAI2 1307/4885ORAI3 1156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.