Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1486303 | 0.93 | NPC1 (0.43) | KIF11NPC1CA1CA2CES1 | |
| SCHEMBL7789704 | 0.80 | MEN1 (0.32) | MEN1KMT2ALMNATDP1 | |
| SCHEMBL2321986 | 0.79 | KIF11 (0.50) | KIF11CYP1A2NPC1CA1CA2 | |
| SCHEMBL1176858 | 0.79 | PTPN1 (0.47) | NPC1ALDH1A1MAPTHTTPTPN1 | |
| SCHEMBL2320050 | 0.72 | DEGS1 (0.49) | NPC1ALDH1A1TSHRHTTTDP1 | |
| SCHEMBL29377536 | 0.72 | CYP1A2 (0.52) | KIF11CYP1A2AHRCES1LMNA | |
| SCHEMBL3952742 | 0.71 | CYP1A2 (0.73) | KIF11CYP1A2NPC1AHRCES1 | |
| SCHEMBL11165087 | 0.71 | CYP1A2 (0.73) | KIF11CYP1A2NPC1AHRCES1 | |
| SCHEMBL28215 | 0.71 | CYP1A2 (0.73) | KIF11CYP1A2NPC1AHRCES1 | |
| SCHEMBL428216 | 0.70 | MEN1 (0.48) | KIF11CYP1A2NPC1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |