Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2321986 | 0.93 | KIF11 (0.50) | MEN1KMT2ALMNATDP1MAPT | |
| SCHEMBL7789704 | 0.88 | MEN1 (0.32) | MEN1KMT2ALMNATDP1 | |
| SCHEMBL5537273 | 0.81 | TSHR (0.43) | MEN1KMT2ALMNAMAPTCA1 | |
| SCHEMBL21836010 | 0.80 | ALDH1A1 (0.68) | MEN1KMT2ALMNATDP1MAPT | |
| SCHEMBL222552 | 0.77 | ALDH1A1 (0.52) | MEN1KMT2ALMNATDP1MAPT | |
| SCHEMBL1318227 | 0.76 | ALDH1A1 (0.44) | MEN1KMT2ALMNAMAPTCA1 | |
| SCHEMBL10804520 | 0.76 | ALDH1A1 (0.46) | MEN1KMT2ALMNATDP1MAPT | |
| SCHEMBL1486303 | 0.76 | NPC1 (0.43) | MEN1KMT2ALMNATDP1MAPT | |
| SCHEMBL1712020 | 0.76 | MAPT (0.46) | MEN1KMT2ALMNATDP1MAPT | |
| SCHEMBL515528 | 0.76 | MEN1 (0.43) | MEN1KMT2ALMNAMAPTCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 933 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190330192-A1 | SUBSTITUTED AZOLYLPYRROLONES AND AZOLYLHYDANTOINS AND SALTS THEREOF AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES | BAYER AKTIENGESELLSCHAFT (DE) | 2019-10-31 | — | — | US | claimed |
| EP-3558976-A1 | SUBSTITUTED AZOLYLPYRROLONES AND AZOLYLHYDANTOINES AND SALTS THEREOF AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES | Bayer CropScience Aktiengesellschaft (DE) | 2019-10-30 | — | — | EP | claimed |
| CN-104262267-B9 | PGI2 receptor modulators for the treatment of prostacyclin (PGI2) receptor-related disorders | 艾尼纳制药公司 | 2019-04-12 | — | — | CN | claimed |
| CN-104262267-B | For treating the PGI2 receptor modulators of prostacyclin (PGI2) receptor associate disorder | 艾尼纳制药公司 | 2019-02-26 | — | — | CN | claimed |
| WO-2015187082-A1 | NEW PLASMA LIPID LOWERING AGENTS | LIPIGON PHARMACEUTICALS AB (SE) | 2015-12-10 | — | — | WO | claimed |
| US-RE44048-E1 | 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-YL]benzenesulfonamide for the treatment of inflammation or an inflammation-associated disorder | G.D. SEARLE LLC (US) | 2013-03-05 | — | — | US | claimed |
| CN-102036659-A | PGI2 receptor modulators for the treatment of prostacyclin receptor-related disorders | ARENA PHARM INC | 2011-04-27 | — | — | CN | claimed |
| EP-1135239-B1 | WOOD PRESERVATIVE FORMULATIONS | HICKSON INTERNAT PLC (GB) | 2008-02-06 | — | — | EP | claimed |
| US-7217723-B2 | Substituted benzothiophenes, e.g., 7Z)-7-hydroxyimino-4,5,6,7-tetrahydro-benzo[b]thiophene-3-sulfonic acid [2-(4-fluorophenyl)-2-hydroxyethyl]-methyl-amide; treating allergies such as atopic dermatitis, allergic coryza, bronchial asthma, hypersensitive pneumoniac and pulmonary aspergillosis. | EISAI CO., LTD. (JP) | 2007-05-15 | — | — | US | claimed |
| US-20060160791-A1 | Wood preservative formulations | WILLIAMS GARETH | 2006-07-20 | — | — | US | claimed |
| US-4675044-A | DEFOLIANTS | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1987-06-23 | — | — | US | claimed |
| US-4569690-A | HERBICIDES, FUNGICIDES, PLANT DESSICANTS, DEFOLIANTS | UNIROYAL, INC. (US) | 1986-02-11 | — | — | US | claimed |
| US-4509948-A | Cationic mono- and dis-azo dyestuffs, and their preparation and use for dyeing paper and cationic dyeable substrates | BAYER AKTIENGESELLSCHAFT (DE) | 1985-04-09 | — | — | US | claimed |
| EP-0104940-A1 | 3-Aryl-5,6-dihydro-1,4,2-oxathiazines and their oxides | UNIROYAL, INC. (US) | 1984-04-04 | — | — | EP | claimed |
| EP-0012112-B1 | PRESSURE-SENSITIVE OR HEAT-SENSITIVE RECORDING MATERIAL | CIBA-GEIGY AG (CH) | 1983-10-05 | — | — | EP | claimed |
| US-4291901-A | Pressure-sensitive or heat-sensitive recording material | CIBA-GEIGY CORPORATION (US) | 1981-09-29 | — | — | US | claimed |
| EP-0012112-A1 | Pressure-sensitive or heat-sensitive recording material | CIBA-GEIGY AG (CH) | 1980-06-11 | — | — | EP | claimed |
| US-4006163-A | POLYESTERS | CIBA-GEIGY CORPORATION (US) | 1977-02-01 | — | — | US | claimed |
| US-4002635-A | FOR COLORING PLASTICS AND LACQUERS | CIBA-GEIGY CORPORATION (US) | 1977-01-11 | — | — | US | claimed |
| US-3954830-A | Yellow methine dyes for hydrophobic textile material | AMERICAN ANILINE PRODUCTS, INC. (US) | 1976-05-04 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160791-A1 | Wood preservative formulations | ATL3, WIZ, NNT | MEN1 2283/4885KMT2A 1557/4885LMNA 143/4885 |
| US-20190330192-A1 | SUBSTITUTED AZOLYLPYRROLONES AND AZOLYLHYDANTOINS AND SALTS THEREOF AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES | AGPS, AASDHPPT, HPD | MEN1 2887/4885KMT2A 872/4885LMNA 4727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.