Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL428216 | 0.93 | MEN1 (0.48) | KIF11MEN1KMT2ALMNATDP1 | |
| SCHEMBL7789704 | 0.82 | MEN1 (0.32) | MEN1KMT2ALMNATDP1 | |
| SCHEMBL1176858 | 0.81 | PTPN1 (0.47) | MAPTNPC1RAB9AHTTSMN1; SMN2 | |
| SCHEMBL2322244 | 0.79 | KIF11 (0.48) | KIF11MEN1KMT2ALMNATDP1 | |
| SCHEMBL14471634 | 0.77 | RAPGEF4 (0.38) | MEN1KMT2AMAPTPOLBRAB9A | |
| SCHEMBL2322131 | 0.77 | AURKA (0.55) | KIF11MEN1KMT2ALMNAMAPT | |
| SCHEMBL5537273 | 0.75 | TSHR (0.43) | KIF11MEN1KMT2ALMNAMAPT | |
| SCHEMBL21836010 | 0.74 | ALDH1A1 (0.68) | MEN1KMT2ALMNATDP1MAPT | |
| SCHEMBL2360450 | 0.74 | EGLN1 (0.44) | MEN1KMT2AMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL15178042 | 0.74 | HPGD (0.67) | KIF11MEN1KMT2ALMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |