SCHEMBL2322367

SCHEMBL2322367

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)[Sn](OCc1ccccc1)(OCc1ccccc1)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
IDO1 P14902 2/20 0.36
AGXT P21549 1/20 0.35
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
CA1 P00915 3/20 0.32
CA2 P00918 3/20 0.32
KDM4E B2RXH2 1/20 0.32
POLB P06746 1/20 0.32
ALDH1A1 P00352 2/20 0.32
CA9 Q16790 1/20 0.32
CES1 P23141 1/20 0.32
LMNA P02545 1/20 0.32
CYP1A2 P05177 1/20 0.32
PTGS1 P23219 1/20 0.32
SLC6A2 P23975 1/20 0.32
CYP2C19 P33261 1/20 0.32
PTGS2 P35354 1/20 0.32
SLC6A3 Q01959 1/20 0.32
HIF1A Q16665 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2345548 0.93 TSHR (0.36) TSHRIDO1AGXTMEN1KMT2A
SCHEMBL2325875 0.86 TSHR (0.39) TSHRIDO1AGXTMEN1KMT2A
SCHEMBL2325241 0.83 TSHR (0.36) TSHRIDO1AGXTCA1CA2
SCHEMBL2324525 0.83 CES1 (0.36) IDO1CA1CA2ALDH1A1CA9
SCHEMBL2325249 0.77 TSHR (0.38) TSHRIDO1AGXTCA1CA2
SCHEMBL2346569 0.77 TSHR (0.34) TSHRIDO1AGXT
SCHEMBL2328694 0.75 TSHR (0.35) TSHRIDO1AGXTALDH1A1LMNA
SCHEMBL2328701 0.71 TSHR (0.43) TSHRIDO1AGXTCA1CA2
SCHEMBL2346576 0.71 TSHR (0.35) TSHRIDO1AGXT
SCHEMBL22164143 0.70 TSHR (0.41) TSHRIDO1AGXTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1760085-B1 PROCESS FOR PRODUCTION OF ALKYLTIN ALKOXIDES ASAHI KASEI CHEMICALS CORP (JP) 2014-02-26 EP disclosed
EP-1987881-B1 METHOD FOR SEPARATION AND COLLECTION OF DIALKYL TIN DIALKOXIDE ASAHI KASEI CHEMICALS CORP (JP) 2011-08-17 EP disclosed
US-7842828-B2 Method for separating out and recovering dialkyltin dialkoxide ASAHI KASEI CHEMICALS CORPORATION (JP) 2010-11-30 US disclosed
US-20100160662-A1 Method for Separating Out and Recovering Dialkyltin Dialkoxide ASAHI KASEI KABUSHIKI KAISHA (JP) 2010-06-24 US disclosed
US-7541482-B2 Process for production of alkyltin alkoxides ASAHI KASEI CHEMICALS CORPORATION (JP) 2009-06-02 US disclosed
US-20080275262-A1 Process for Production of Alkyltin Alkoxides ASAHI KASEI CHEMICALS CORPORATION (JP) 2008-11-06 US disclosed
EP-1987881-A1 METHOD FOR SEPARATION AND COLLECTION OF DIALKYL TIN DIALKOXIDE Asahi Kasei Chemicals Corporation (JP) 2008-11-05 EP disclosed
EP-1760085-A1 PROCESS FOR PRODUCTION OF ALKYLTIN ALKOXIDES Asahi Kasei Chemicals Corporation (JP) 2007-03-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100160662-A1 Method for Separating Out and Recovering Dialkyltin Dialkoxide ALOX5, ALOX15B, ALOX15 TSHR 3272/4885IDO1 2152/4885AGXT 449/4885
US-20080275262-A1 Process for Production of Alkyltin Alkoxides ALK, MOGAT2, SOAT2 TSHR 349/4885IDO1 1650/4885AGXT 98/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.