Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 14/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7385877 | 0.85 | ACHE (0.52) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL10927214 | 0.84 | ACHE (0.64) | ACHE | |
| SCHEMBL10778878 | 0.82 | ACHE (0.53) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL21068069 | 0.82 | ACHE (0.61) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7570219 | 0.82 | ACHE (0.61) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7770088 | 0.81 | ACHE (0.52) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL15549930 | 0.81 | HTT (0.56) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL25349245 | 0.81 | CYP1A2 (0.53) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL24131327 | 0.81 | LMNA (0.48) | ACHE | |
| SCHEMBL12417367 | 0.80 | ACHE (0.61) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021072140-A1 | PRODRUGS OF MYELOPEROXIDASE INHIBITORS | BIOHAVEN THERAPEUTICS LTD. (US) | 2021-04-15 | — | — | WO | disclosed |