Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.39 |
| ▸ | AURKA | O14965 | 2/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.39 |
| ▸ | RET | P07949 | 2/20 | 0.39 |
| ▸ | IGF1R | P08069 | 2/20 | 0.39 |
| ▸ | PIM1 | P11309 | 2/20 | 0.39 |
| ▸ | CLK2 | P49760 | 2/20 | 0.39 |
| ▸ | GSK3A | P49840 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | PRKX | P51817 | 2/20 | 0.39 |
| ▸ | BTK | Q06187 | 2/20 | 0.39 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.39 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.39 |
| ▸ | TAOK1 | Q7L7X3 | 2/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14697594 | 0.79 | CSNK2A1 (0.37) | CSNK2A1DYRK1AAURKADAPK3PRKD3 | |
| SCHEMBL3147727 | 0.79 | DAO (0.44) | CSNK2A1DYRK1AAURKADAPK3PRKD3 | |
| SCHEMBL3151345 | 0.75 | AURKA (0.34) | CSNK2A1DYRK1AAURKADAPK3PRKD3 | |
| SCHEMBL23270586 | 0.75 | CSNK1A1 (0.37) | CSNK2A1CLK4CSNK1A1LRRK2IP6K1 | |
| SCHEMBL127024 | 0.70 | AXL (0.48) | CSNK2A1DYRK1AAURKADAPK3PRKD3 | |
| SCHEMBL15803743 | 0.68 | CSNK2A1 (0.34) | CSNK2A1DYRK1AAURKADAPK3PRKD3 | |
| Water SCHEMBL10628541 | 0.68 | AXL (0.47) | CSNK2A1DYRK1AAURKADAPK3PRKD3 | |
| SCHEMBL20471716 | 0.68 | NUDT1 (0.46) | LRRK2RAB9AADORA2AMEN1KMT2A | |
| SCHEMBL9081 | 0.67 | CHEK1 (0.42) | CSNK2A1DYRK1AAURKADAPK3PRKD3 | |
| SCHEMBL30942632 | 0.67 | CHEK1 (0.42) | CSNK2A1DYRK1AAURKADAPK3PRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110191882-B | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | 株式会社大熊制药 | 2022-09-13 | — | — | CN | disclosed |
| US-10981917-B2 | Heterocyclic compound, its preparation method, and pharmaceutical composition comprising the same | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2021-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10981917-B2 | Heterocyclic compound, its preparation method, and pharmaceutical composition comprising the same | RNASE1, AARS1, DHPS | CSNK2A1 1622/4885DYRK1A 4802/4885AURKA 4744/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.