Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | GLS | O94925 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PLEC | Q15149 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11051509 | 0.85 | MTNR1A (0.50) | L3MBTL1MTNR1AMTNR1BTDP1 | |
| SCHEMBL27365553 | 0.84 | MTNR1A (0.59) | L3MBTL1MAPTTSHRMTNR1AMTNR1B | |
| SCHEMBL9863289 | 0.83 | MTNR1A (0.52) | L3MBTL1MTNR1AMTNR1BALDH1A1KDM4E | |
| SCHEMBL7890168 | 0.82 | TBXAS1 (0.59) | L3MBTL1MAPTNPSR1TSHRGLA | |
| SCHEMBL7847681 | 0.82 | TSHR (0.58) | L3MBTL1MAPTNPSR1TSHRGLA | |
| SCHEMBL30104114 | 0.82 | TSHR (0.58) | L3MBTL1MAPTNPSR1TSHRGLA | |
| SCHEMBL23478172 | 0.82 | L3MBTL1 (0.70) | L3MBTL1MAPTNPSR1TSHRGLA | |
| SCHEMBL31274509 | 0.82 | L3MBTL1 (0.70) | L3MBTL1MAPTNPSR1TSHRGLA | |
| SCHEMBL23241802 | 0.80 | MTNR1A (0.46) | L3MBTL1TSHRMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL16410290 | 0.80 | CFD (0.41) | L3MBTL1MAPTMTNR1AMTNR1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021072198-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |