Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 3/20 | 0.36 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1583311 | 0.97 | KDM4E (0.43) | KDM4ESMN1; SMN2ALDH1A1LMNACYP1A2 | |
| SCHEMBL1583841 | 0.80 | ITGB1 (0.30) | — | |
| SCHEMBL1583857 | 0.78 | KCNQ3 (0.32) | SMN1; SMN2ALDH1A1EPHX2 | |
| SCHEMBL1583688 | 0.78 | LMNA (0.31) | LMNACYP1A2CYP2D6SCN1ASCN2A | |
| SCHEMBL5682510 | 0.72 | CYP2D6 (0.33) | KDM4ESMN1; SMN2ALDH1A1LMNACYP1A2 | |
| SCHEMBL19210480 | 0.72 | CYP2D6 (0.48) | SMN1; SMN2ALDH1A1CYP2D6MEN1KMT2A | |
| SCHEMBL4594860 | 0.71 | TP53 (0.38) | KDM4ESMN1; SMN2ALDH1A1LMNAEPHX1 | |
| SCHEMBL1583369 | 0.71 | ADRB2 (0.36) | — | |
| SCHEMBL2548071 | 0.69 | CYP2D6 (0.39) | KDM4ESMN1; SMN2ALDH1A1LMNACYP1A2 | |
| SCHEMBL3547551 | 0.69 | KDM4E (0.50) | KDM4ESMN1; SMN2ALDH1A1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011097491-A1 | BENZIMIDAZOLE ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-08-11 | — | — | WO | disclosed |