Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989269 | 0.84 | LMNA (0.83) | LMNAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL7989530 | 0.84 | LMNA (0.83) | LMNAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL11356824 | 0.84 | LMNA (0.83) | LMNAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL1045922 | 0.84 | LMNA (0.83) | LMNAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL2325333 | 0.84 | LMNA (0.65) | LMNAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL18058256 | 0.82 | LMNA (0.62) | LMNAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL3030830 | 0.81 | SIGMAR1 (0.69) | LMNAALDH1A1POLBKMT2A | |
| SCHEMBL5544542 | 0.79 | CHKA (0.56) | LMNAALDH1A1POLBKMT2AMAPK1 | |
| SCHEMBL1045984 | 0.79 | ALDH1A1 (0.74) | LMNAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL1045595 | 0.79 | ALDH1A1 (0.74) | LMNAALDH1A1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |