Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOX | P28300 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ACVR2A | P27037 | 2/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | MAT2A | P31153 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28781272 | 0.81 | LOX (0.41) | LOXLOXL2SORT1GABRA1GABRG2 | |
| SCHEMBL677234 | 0.80 | NOS3 (0.52) | LOXLOXL2SORT1GABRA1GABRG2 | |
| SCHEMBL31121348 | 0.80 | NOS3 (0.52) | LOXLOXL2SORT1GABRA1GABRG2 | |
| SCHEMBL23214996 | 0.79 | SORT1 (0.43) | LOXLOXL2SORT1NR2E1HCRTR1 | |
| SCHEMBL14768850 | 0.79 | LOX (0.46) | LOXLOXL2SORT1GABRA1GABRG2 | |
| SCHEMBL30947592 | 0.79 | LOX (0.46) | LOXLOXL2SORT1GABRA1GABRG2 | |
| SCHEMBL29664774 | 0.77 | SORT1 (0.37) | LOXLOXL2SORT1GABRA1GABRG2 | |
| SCHEMBL30265238 | 0.75 | SORT1 (0.38) | LOXLOXL2SORT1NR2E1HCRTR1 | |
| SCHEMBL803416 | 0.74 | LOX (0.48) | LOXLOXL2SORT1GABRA1GABRG2 | |
| SCHEMBL23215152 | 0.73 | LOX (0.45) | LOXLOXL2SORT1GABRA1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021071843-A1 | MUSCARINIC ACETYLCHOLINE M1 RECEPTOR ANTAGONISTS | Pipeline Therapeutics, Inc. (US) | 2021-04-15 | — | — | WO | disclosed |