Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.52 |
| ▸ | NOS2 | P35228 | 1/20 | 0.52 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.50 |
| ▸ | LOX | P28300 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.42 |
| ▸ | GAK | O14976 | 4/20 | 0.42 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.42 |
| ▸ | NLK | Q9UBE8 | 2/20 | 0.42 |
| ▸ | STK16 | O75716 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31121348 | 1.00 | NOS3 (0.52) | NOS3NOS2SORT1LOXLOXL2 | |
| SCHEMBL14768850 | 0.86 | LOX (0.46) | NOS3NOS2SORT1LOXLOXL2 | |
| SCHEMBL30947592 | 0.86 | LOX (0.46) | NOS3NOS2SORT1LOXLOXL2 | |
| SCHEMBL15616201 | 0.82 | NUDT1 (0.47) | NOS3NOS2SORT1LOXLOXL2 | |
| SCHEMBL803416 | 0.82 | LOX (0.48) | NOS3NOS2SORT1LOXLOXL2 | |
| SCHEMBL13020077 | 0.81 | NOS3 (0.48) | NOS3NOS2SORT1NPC1CASP3 | |
| SCHEMBL3149643 | 0.81 | NOS3 (0.48) | NOS3NOS2SORT1NPC1CASP3 | |
| SCHEMBL23232007 | 0.80 | LOX (0.41) | NOS3NOS2SORT1LOXLOXL2 | |
| SCHEMBL29664692 | 0.80 | LOX (0.45) | NOS3NOS2SORT1LOXLOXL2 | |
| SCHEMBL23215152 | 0.80 | LOX (0.45) | NOS3NOS2SORT1LOXLOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12441725-B2 | ISO-citrate dehydrogenase (IDH) inhibitor | ZHEJIANG METON PHARMACEUTICAL CO., LTD (CN) | 2025-10-14 | — | — | US | disclosed |
| US-12077505-B2 | Preparation of sulfonamide herbicide process intermediates | CORTEVA AGRISCIENCE LLC (US) | 2024-09-03 | — | — | US | disclosed |
| US-20240116917-A1 | ISO-CITRATE DEHYDROGENASE (IDH) INHIBITOR | ZHEJIANG METON PHARMACEUTICAL CO., LTD (CN) | 2024-04-11 | — | — | US | disclosed |
| CN-117050009-A | Preparation method of 4-trifluoromethyl pyridine intermediate core parent nucleus and derivatives thereof | 台州臻挚生物科技有限公司 | 2023-11-14 | — | — | CN | disclosed |
| EP-3784669-B1 | PTERIDINONE COMPOUNDS AND USES THEREOF | VERTEX PHARMA (US) | 2023-10-25 | — | — | EP | disclosed |
| CN-116390917-A | MRGX2 antagonists | 葛兰素史密斯克莱知识产权发展有限公司 | 2023-07-04 | — | — | CN | disclosed |
| US-20220024873-A1 | PREPARATION OF SULFONAMIDE HERBICIDE PROCESS INTERMEDIATES | Geneva Agriscience LLC (US) | 2022-01-27 | — | — | US | disclosed |
| US-11174250-B2 | Substituted carboxamides as inhibitors of WDR5 protein-protein binding | Propellon Therapeutics Inc. (CA) | 2021-11-16 | — | — | US | disclosed |
| EP-3902785-A1 | PREPARATION OF SULFONAMIDE HERBICIDE PROCESS INTERMEDIATES | Corteva Agriscience LLC (US) | 2021-11-03 | — | — | EP | disclosed |
| CN-113272277-A | Sulfonamide herbicide process intermediates preparation | 科迪华农业科技有限责任公司 | 2021-08-17 | — | — | CN | disclosed |
| EP-1304325-A1 | 5-(M-CYANOBENZYLAMINO)PYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-20020111361-A1 | N- (5, 7-dimethoxy [1, 2, 4] triazolo [1, 5-a] pyrimidin-2-yl) arylsulfonamide compounds and their use as herbicides | CORTEVA AGRISCIENCE LLC | 2002-08-15 | — | — | US | disclosed |
| US-6303814-B1 | N-[1,2,4]triazoloazinyl) benzenesulfonamide and pyridinesulfonamide compounds and their use as herbicides | DOW AGROSCIENCES LLC | 2001-10-16 | — | — | US | disclosed |
| EP-0877745-B1 | N-( 1,2,4] TRIAZOLOAZINYL)BENZENESULFONAMIDE AND PYRIDINESULFONAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2001-07-25 | — | — | EP | disclosed |
| US-6130335-A | N-([1,2,4]triazoloazinyl) benzenesulfonamide and pyridinesulfonamide compounds and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2000-10-10 | — | — | US | disclosed |
| US-6005108-A | POST-EMERGENCE TOTAL VEGETATION CONTROL OR SELECTIVE CONTROL OF WEEDS IN WHEAT, RICE AND OIL-SEED RAPE CROPS | JOHNSON TIMOTHY C (US) | 1999-12-21 | — | — | US | disclosed |
| US-5965490-A | NOVEL COMPOUNDS WITH IMPROVED SELECTIVITY TO VALUABLE CROPS AND IMPROVED TOXICOLOGICAL AND ENVIRONMENTAL ATTRIBUTES; APPLYING TO CONTROL WEEDS BY EITHER PREEMERGENCE OR POSTEMERGENCE APPLICATION | DOW AGROSCIENCES LLC (US) | 1999-10-12 | — | — | US | disclosed |
| US-5858924-A | N-( 1, 2, 4! triazoloazinyl) benzenesulfonamide and pyridinesulfonamide compounds and their use as herbicides | DOW AGROSCIENCES LLC (US) | 1999-01-12 | — | — | US | disclosed |
| EP-0877745-A2 | N-( 1,2,4] TRIAZOLOAZINYL)BENZENESULFONAMIDE AND PYRIDINESULFONAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES | Dow Agrosciences LLC (US) | 1998-11-18 | — | — | EP | disclosed |
| WO-1998013367-A1 | N-([1,2,4] TRIAZOLOAZINYL)BENZENESULFONAMIDE AND PYRIDINESULFONAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 1998-04-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11174250-B2 | Substituted carboxamides as inhibitors of WDR5 protein-protein binding | WDR5, WDR82, WDR1 | NOS3 4490/4885NOS2 4385/4885SORT1 4704/4885 |
| US-20240116917-A1 | ISO-CITRATE DEHYDROGENASE (IDH) INHIBITOR | IDH2, IDH3A, IDH1 | NOS3 2641/4885NOS2 2010/4885SORT1 4842/4885 |
| US-20020111361-A1 | N- (5, 7-dimethoxy [1, 2, 4] triazolo [1, 5-a] pyrimidin-2-yl) arylsulfonamide compounds and their use as herbicides | DDT, DDO, DAO | NOS3 3505/4885NOS2 3748/4885SORT1 4346/4885 |
| US-12077505-B2 | Preparation of sulfonamide herbicide process intermediates | ORMDL3, STS, CBR3 | NOS3 1269/4885NOS2 1403/4885SORT1 3748/4885 |
| US-20220024873-A1 | PREPARATION OF SULFONAMIDE HERBICIDE PROCESS INTERMEDIATES | ORMDL3, STS, CBR3 | NOS3 1269/4885NOS2 1403/4885SORT1 3748/4885 |
| US-12441725-B2 | ISO-citrate dehydrogenase (IDH) inhibitor | IDH2, IDH3A, IDH1 | NOS3 2641/4885NOS2 2010/4885SORT1 4842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.