Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORT1 | Q99523 | 1/20 | 0.37 |
| ▸ | LOX | P28300 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28781272 | 0.78 | LOX (0.41) | SORT1LOXLOXL2ADRB2HCRTR1 | |
| SCHEMBL23232007 | 0.77 | LOX (0.41) | SORT1LOXLOXL2HCRTR1HCRTR2 | |
| SCHEMBL23214996 | 0.76 | SORT1 (0.43) | SORT1LOXLOXL2HCRTR1HCRTR2 | |
| SCHEMBL30265238 | 0.74 | SORT1 (0.38) | SORT1LOXLOXL2HCRTR1HCRTR2 | |
| SCHEMBL30947592 | 0.73 | LOX (0.46) | SORT1LOXLOXL2HCRTR1HCRTR2 | |
| SCHEMBL14768850 | 0.73 | LOX (0.46) | SORT1LOXLOXL2HCRTR1HCRTR2 | |
| SCHEMBL677234 | 0.71 | NOS3 (0.52) | SORT1LOXLOXL2ADRB2HCRTR1 | |
| SCHEMBL31121348 | 0.71 | NOS3 (0.52) | SORT1LOXLOXL2ADRB2HCRTR1 | |
| SCHEMBL803416 | 0.69 | LOX (0.48) | SORT1LOXLOXL2AAK1GABRA1 | |
| SCHEMBL24094523 | 0.69 | SORT1 (0.46) | SORT1LOXLOXL2HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114729044-A | Muscarinic acetylcholine M1Receptor antagonists | 帕珀莱恩医疗公司 | 2022-07-08 | — | — | CN | disclosed |