Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.47 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.47 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.47 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.46 |
| ▸ | CTSG | P08311 | 4/20 | 0.46 |
| ▸ | CTRB1 | P17538 | 4/20 | 0.46 |
| ▸ | CMA1 | P23946 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2327345 | 0.93 | CYP26A1 (0.50) | BCHEACHECACNA1FCACNA1DCACNA1S | |
| SCHEMBL2332966 | 0.89 | NAAA (0.45) | BCHEACHECACNA1FCACNA1DCACNA1S | |
| SCHEMBL27822915 | 0.89 | NAAA (0.45) | BCHEACHECACNA1FCACNA1DCACNA1S | |
| SCHEMBL2327265 | 0.89 | CYP26A1 (0.47) | BCHEACHEPRSS1CTSGCTRB1 | |
| SCHEMBL2328548 | 0.86 | CA1 (0.51) | PRSS1CTSGCTRB1CMA1CA2 | |
| SCHEMBL2331418 | 0.85 | CLPP (0.44) | TDP1GAAALDH1A1 | |
| SCHEMBL2329799 | 0.83 | CNR2 (0.54) | TDP1LMNAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL2333174 | 0.83 | ALDH1A1 (0.52) | TDP1RAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28814272 | 0.81 | TAS1R3 (0.60) | PRSS1CTSGCTRB1CMA1CYP26A1 | |
| SCHEMBL2505263 | 0.81 | CYP26A1 (0.51) | PRSS1CTSGCTRB1CMA1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2356979-B1 | ANTI-WRINKLE AGENTS | POLA CHEM IND INC (JP) | 2017-10-25 | — | — | EP | disclosed |
| EP-3173063-A1 | ANTI-WRINKLE AGENTS | Pola Chemical Industries Inc. (JP) | 2017-05-31 | — | — | EP | disclosed |
| US-8835498-B2 | Anti-wrinkle agents | POLA CHEMICAL INDUSTRIES INC. (JP) | 2014-09-16 | — | — | US | disclosed |
| US-20110245343-A1 | ANTI-WRINKLE AGENTS | POLA CHEMICAL INDUSTRIES INC. (JP) | 2011-10-06 | — | — | US | disclosed |
| EP-2356979-A1 | ANTI-WRINKLE AGENTS | Pola Chemical Industries Inc. (JP) | 2011-08-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110245343-A1 | ANTI-WRINKLE AGENTS | GLA, H1-4, H1-3 | BCHE 3708/4885ACHE 4121/4885CACNA1F 2090/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.