Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 4/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.42 |
| ▸ | HRH2 | P25021 | 4/20 | 0.38 |
| ▸ | HRH1 | P35367 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23121052 | 0.85 | CTPS1 (0.43) | OPRD1OPRK1POLBKCNH2OPRM1 | |
| SCHEMBL22749260 | 0.80 | KMT2A (0.44) | OPRD1OPRK1KDM4EALDH1A1KCNH2 | |
| SCHEMBL22762433 | 0.79 | OPRM1 (0.39) | OPRD1OPRK1KDM4EKCNH2OPRM1 | |
| SCHEMBL22749259 | 0.78 | OPRM1 (0.52) | OPRD1OPRK1POLBSMN1; SMN2KDM4E | |
| SCHEMBL28786542 | 0.75 | FFAR4 (0.34) | OPRD1OPRK1POLBKDM4EALDH1A1 | |
| SCHEMBL28944831 | 0.74 | ATM (0.42) | OPRD1OPRK1POLB | |
| SCHEMBL9037444 | 0.69 | OPRD1 (0.51) | OPRD1OPRK1HRH2HRH1LMNA | |
| SCHEMBL22758510 | 0.68 | FFAR4 (0.36) | MEN1KMT2A | |
| SCHEMBL22995548 | 0.67 | OPRM1 (0.41) | OPRD1OPRK1POLBALDH1A1KCNH2 | |
| SCHEMBL1447090 | 0.67 | OPRD1 (0.56) | OPRD1OPRK1LMNAPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3806855-A1 | GLP-1 RECEPTOR AGONISTS AND USES THEREOF | Pfizer Inc. (US) | 2021-04-21 | — | — | EP | disclosed |