Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | HNF4A | P41235 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7012982 | 0.84 | ALDH1A1 (0.43) | PDCD1CD274ALDH1A1HSD17B10HPGD | |
| SCHEMBL31376578 | 0.84 | ALDH1A1 (0.43) | PDCD1CD274ALDH1A1HSD17B10HPGD | |
| SCHEMBL7012979 | 0.84 | ALDH1A1 (0.43) | PDCD1CD274ALDH1A1HSD17B10HPGD | |
| SCHEMBL18812668 | 0.80 | HDAC4 (0.40) | PDCD1CD274HNF4AALDH1A1HSD17B10 | |
| SCHEMBL8418126 | 0.80 | PDCD1 (0.41) | PDCD1CD274HNF4AALDH1A1HSD17B10 | |
| SCHEMBL8416365 | 0.77 | PDCD1 (0.39) | PDCD1CD274HNF4AALDH1A1HSD17B10 | |
| SCHEMBL7109459 | 0.76 | HPGD (0.41) | ALDH1A1HSD17B10HPGDBCL2L1KMT2A | |
| SCHEMBL1549219 | 0.75 | LMNA (0.39) | LMNA | |
| SCHEMBL11314594 | 0.75 | CA1 (0.43) | PDCD1CD274HNF4AALDH1A1HPGD | |
| SCHEMBL7409018 | 0.73 | LMNA (0.52) | PDCD1CD274HNF4AALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200276778-A1 | Photochromic Lens | VISION EASE, LP (US) | 2020-09-03 | — | — | US | disclosed |
| US-10052849-B2 | Photochromic polyurethane laminate | VISION EASE, LP (US) | 2018-08-21 | — | — | US | disclosed |
| US-9981453-B2 | Photochromic polyurethane laminate | VISION EASE, LP (US) | 2018-05-29 | — | — | US | disclosed |
| US-9981452-B2 | Photochromic polyurethane laminate | VISION EASE, LP (US) | 2018-05-29 | — | — | US | disclosed |
| US-20160370516-A1 | Photochromic Polyurethane Laminate | VISION EASE, LP (US) | 2016-12-22 | — | — | US | disclosed |
| US-20160370517-A1 | Photochromic Polyurethane Laminate | VISION EASE, LP (US) | 2016-12-22 | — | — | US | disclosed |
| US-20160370518-A1 | Photochromic Polyurethane Laminate | VISION EASE, LP (US) | 2016-12-22 | — | — | US | disclosed |
| EP-2955567-A1 | PHOTOCHROMIC POLYURETHANE LAMINATE | Insight Equity A.P.X., LP (US) | 2015-12-16 | — | — | EP | disclosed |
| EP-2955568-A1 | Photochromic polyurethane laminate | Insight Equity A.P.X., LP (US) | 2015-12-16 | — | — | EP | disclosed |
| EP-1673655-B1 | PHOTOCHROMIC POLYURETHANE LAMINATE | INSIGHT EQUITY A P X LP (US) | 2015-05-06 | — | — | EP | disclosed |
| US-6659608-B2 | Polarizing optical article | YAMAMOTO KOGAKU CO., LTD. (JP) | 2003-12-09 | — | — | US | disclosed |
| US-6613433-B2 | Composite equipped with a polarizing plate holding a polarizer sheet layer between two protective sheet layers, wherein the polarizing sheet layer has on one side thereof at least two layers, in a body, constructed of materials different each | YAMAMOTO KOGAKU CO., LTD. (JP) | 2003-09-02 | — | — | US | disclosed |
| EP-1279993-A1 | POLARIZING OPTICAL ARTICLE | Yamamoto Kogaku Co., Ltd. (JP) | 2003-01-29 | — | — | EP | disclosed |
| US-20020136897-A1 | TRANSPARENT OPTICAL ARTICLE | YAMAMOTO KOGAKU CO., LTD. (JP) | 2002-09-26 | — | — | US | disclosed |
| US-20020135735-A1 | Polarizing optical article | YAMAMOTO KOGAKU CO., LTD. (JP) | 2002-09-26 | — | — | US | disclosed |
| US-6455163-B1 | Transparent optical article | YAMAMOTO KOGAKU CO., LTD. (JP) | 2002-09-24 | — | — | US | disclosed |
| US-20020084023-A1 | Polarizing molded article and process for preparing the same | YAMAMOTO KOGAKU CO., LTD. (JP) | 2002-07-04 | — | — | US | disclosed |
| EP-1217397-A2 | Polarizing molded article and process for preparing the same | YAMAMOTO KOGAKU CO., LTD. (JP) | 2002-06-26 | — | — | EP | disclosed |
| US-20020044352-A1 | Polarizing optical composite and polarizing lens | YAMAMOTO KOGAKU CO., LTD. (JP) | 2002-04-18 | — | — | US | disclosed |
| EP-1193535-A1 | TRANSPARENT OPTICAL ARTICLE | Yamamoto Kogaku Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |