Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7319411 | 0.84 | GAA (0.50) | KDM4EALDH1A1SLC9A1CYP1A2CYP2C19 | |
| SCHEMBL2318440 | 0.80 | CYP1A1 (0.42) | CYP1A2CYP2C19NOTUMPRMT1CYP1A1 | |
| SCHEMBL11622587 | 0.76 | PRMT1 (0.54) | KDM4EALDH1A1SLC9A1CYP1A2CYP2C19 | |
| SCHEMBL1660370 | 0.76 | KDM4E (0.34) | KDM4EALDH1A1SLC9A1CYP1A2CYP2C19 | |
| SCHEMBL2324206 | 0.76 | SLC9A1 (0.48) | KDM4EALDH1A1SLC9A1GAAMAPK1 | |
| SCHEMBL4493820 | 0.76 | RAB9A (0.54) | KDM4EALDH1A1SLC9A1CYP1A2CYP2C19 | |
| SCHEMBL1199113 | 0.75 | KDM4E (0.67) | KDM4EALDH1A1SLC9A1CYP1A2CYP2C19 | |
| SCHEMBL1661873 | 0.75 | NOTUM (0.46) | KDM4EALDH1A1NOTUM | |
| SCHEMBL1222870 | 0.74 | SLC9A1 (0.67) | KDM4EALDH1A1SLC9A1CYP1A2CYP2C19 | |
| SCHEMBL2346044 | 0.74 | ALDH1A1 (0.46) | ALDH1A1SLC9A1CYP2C19RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |