Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Pyridine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.90 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.90 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.90 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL10552175 | 1.00 | TSHR (0.90) | TSHRNAPRTTDP1NOTUMSLC6A2 | |
| Pyridine SCHEMBL69088 | 1.00 | — | — | |
| Pyridine SCHEMBL29517174 | 1.00 | TSHR (0.90) | TSHRNAPRTTDP1NOTUMSLC6A2 | |
| Pyridine SCHEMBL2323896 | 1.00 | — | — | |
| Pyridine SCHEMBL10752757 | 1.00 | — | — | |
| Pyridine SCHEMBL563923 | 1.00 | TSHR (0.90) | TSHRNAPRTTDP1NOTUMSLC6A2 | |
| Pyridine SCHEMBL28726810 | 0.95 | TSHR (0.82) | TSHRNAPRTTDP1NOTUMSLC6A2 | |
| Pyridine SCHEMBL28479225 | 0.95 | TSHR (0.82) | TSHRNAPRTTDP1NOTUMSLC6A2 | |
| Pyridine SCHEMBL7997339 | 0.95 | — | — | |
| Pyridine SCHEMBL28510953 | 0.95 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4553061-A1 | METHOD FOR PRODUCING FLUORINATED ORGANIC COMPOUND | DAIKIN INDUSTRIES, LTD. (JP) | 2025-05-14 | — | — | EP | disclosed |
| CN-119403778-A | Process for producing fluorinated organic compound | 大金工业株式会社 | 2025-02-07 | — | — | CN | disclosed |
| WO-2024009998-A1 | METHOD FOR PRODUCING FLUORINATED ORGANIC COMPOUND | ダイキン工業株式会社 | 2024-01-11 | — | — | WO | disclosed |
| EP-4223736-A1 | PRODUCTION METHOD FOR FLUORINATED ORGANIC COMPOUND | Daikin Industries, Ltd. (JP) | 2023-08-09 | — | — | EP | disclosed |
| US-20230242468-A1 | PRODUCTION METHOD FOR FLUORINATED ORGANIC COMPOUND | DAIKIN INDUSTRIES, LTD. (JP) | 2023-08-03 | — | — | US | disclosed |
| CN-116249686-A | Process for producing fluorinated organic compound | 大金工业株式会社 | 2023-06-09 | — | — | CN | disclosed |
| US-11377407-B2 | Method for producing difluoromethylene compound | DAIKIN INDUSTRIES, LTD. (JP) | 2022-07-05 | — | — | US | disclosed |
| WO-2022071363-A1 | PRODUCTION METHOD FOR FLUORINATED ORGANIC COMPOUND | ダイキン工業株式会社 | 2022-04-07 | — | — | WO | disclosed |
| US-20210363077-A1 | METHOD FOR PRODUCING DIFLUOROMETHYLENE COMPOUND | DAIKIN INDUSTRIES, LTD. (JP) | 2021-11-25 | — | — | US | disclosed |
| US-11091432-B2 | Composition, fluorinating reagent, and method for producing fluorinated organic compound | DAIKIN INDUSTRIES, LTD. (JP) | 2021-08-17 | — | — | US | disclosed |
| US-6921739-B2 | Anti-microbial and oxidative co-polymer | AQUATIC TREATMENT SYSTEMS, INC. (US) | 2005-07-26 | — | — | US | disclosed |
| US-20050061746-A1 | Anti-microbial and oxidative co-polymer | AQUEOUS SOLUTIONS GLOBAL, LLC | 2005-03-24 | — | — | US | disclosed |
| US-20040245505-A1 | Process for the production of fluorinated organic compounds and fluorinating agents | DAIKIN INDUSTRIES, LTD. (JP) | 2004-12-09 | — | — | US | disclosed |
| US-6784327-B2 | ORGANIC COMPOUNDS HAVING HYDROGEN ATOMS, WHICH SERVE AS STARTING MATERIALS, ARE FLUORINATED USING IF5 | DAIKIN INDUSTRIES, LTD. (JP) | 2004-08-31 | — | — | US | disclosed |
| WO-2002050164-A9 | ANTI-MICROBIAL AND OXIDATIVE CO-POLYMER | AQUATIC TREAT SYSTEMS INC (US) | 2004-06-24 | — | — | WO | disclosed |
| EP-1363963-A1 | ANTI-MICROBIAL AND OXIDATIVE CO-POLYMER | Aquatic Treatment Systems, Inc. (US) | 2003-11-26 | — | — | EP | disclosed |
| US-20030176747-A1 | Process for the production of fluorinated organic compounds and fluorinating agents | DAIKIN INDUSTRIES, LTD. (JP) | 2003-09-18 | — | — | US | disclosed |
| EP-1304316-A1 | PROCESSES FOR THE PRODUCTION OF FLUORINATED ORGANIC COMPOUNDS AND FLUORINATING AGENTS | Daikin Industries, Ltd. (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-20020179542-A1 | Anti-microbial and oxidative co-polymer | AQUATIC TREATMENT SYSTEMS, INC. | 2002-12-05 | — | — | US | disclosed |
| WO-2002050164-A1 | ANTI-MICROBIAL AND OXIDATIVE CO-POLYMER | AQUATIC TREATMENT SYSTEMS, INC. (US) | 2002-06-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11091432-B2 | Composition, fluorinating reagent, and method for producing fluorinated organic compound | IPO5, AFF2, IL5 | TSHR 2383/4885NAPRT 2342/4885TDP1 2523/4885 |
| US-20050061746-A1 | Anti-microbial and oxidative co-polymer | AS3MT, SOD1, SOD3 | TSHR 1375/4885NAPRT 3800/4885TDP1 2803/4885 |
| US-20040245505-A1 | Process for the production of fluorinated organic compounds and fluorinating agents | PFAS, AFF4, AFF1 | TSHR 2577/4885NAPRT 996/4885TDP1 2061/4885 |
| US-20230242468-A1 | PRODUCTION METHOD FOR FLUORINATED ORGANIC COMPOUND | IPO5, PFAS, FBL | TSHR 2710/4885NAPRT 1637/4885TDP1 4037/4885 |
| US-20030176747-A1 | Process for the production of fluorinated organic compounds and fluorinating agents | PFAS, AFF4, AFF1 | TSHR 2577/4885NAPRT 996/4885TDP1 2061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.