SCHEMBL2323918

SCHEMBL2323918

O=S(=O)(c1ccc(Cl)cc1)C(Cl)(Cl)Cl

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.56
CYP3A4 P08684 1/20 0.56
MAPK1 P28482 1/20 0.56
CA1 P00915 4/20 0.52
CA2 P00918 4/20 0.52
CA12 O43570 3/20 0.52
CA3 P07451 3/20 0.52
CA4 P22748 3/20 0.52
CA6 P23280 3/20 0.52
CA5A P35218 3/20 0.52
CA7 P43166 3/20 0.52
CA9 Q16790 3/20 0.52
CA13 Q8N1Q1 3/20 0.52
CA14 Q9ULX7 3/20 0.52
CA5B Q9Y2D0 3/20 0.52
KMT2A Q03164 2/20 0.46
MMP2 P08253 2/20 0.46
MEN1 O00255 1/20 0.46
MMP1 P03956 1/20 0.46
MMP9 P14780 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20572271 0.81 ALDH1A1 (0.52) ALDH1A1CYP3A4MAPK1CA1CA2
SCHEMBL753655 0.80 ALDH1A1 (0.56) ALDH1A1CYP3A4MAPK1CA1CA2
SCHEMBL750671 0.80 ALDH1A1 (0.56) ALDH1A1CYP3A4MAPK1CA1CA2
SCHEMBL11844016 0.79 ALDH1A1 (0.50) ALDH1A1CYP3A4MAPK1CA1CA2
SCHEMBL7940614 0.78 MMP2 (0.45) ALDH1A1CA1CA2KMT2AMMP2
SCHEMBL10083746 0.78 ALDH1A1 (0.61) ALDH1A1CYP3A4MAPK1CA1CA2
SCHEMBL1828426 0.78 ALDH1A1 (0.54) ALDH1A1CYP3A4MAPK1CA1CA2
SCHEMBL7940658 0.78 LMNA (0.52) ALDH1A1CYP3A4CA1CA2CA12
SCHEMBL544875 0.77 TDP1 (0.52) ALDH1A1CA1CA2CA12CA3
SCHEMBL10146076 0.75 ALDH1A1 (0.50) ALDH1A1CYP3A4MAPK1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2356182-B1 RADIATION CURABLE COATING MATERIALS BASF SE (DE) 2015-05-06 EP disclosed
CN-102216400-B Radiation curable coating materials BASF SE 2013-12-18 CN disclosed
US-20130299736-A1 RADIATION-CURABLE COATING MATERIALS BASE SE (DE) 2013-11-14 US disclosed
CN-102216400-A Radiation curable coating materials BASF SE 2011-10-12 CN disclosed
US-20110230617-A1 RADIATION-CURABLE COATING MATERIALS BASF SE (DE) 2011-09-22 US disclosed
EP-2356182-A1 RADIATION CURABLE COATING MATERIALS BASF SE (DE) 2011-08-17 EP disclosed
CN-101069129-B Radiation-curable coating substances BASF AG 2010-12-08 CN disclosed
US-20100126386-A1 RADIATION-CURABLE COATING SUBSTANCES BASF AKTIENGESELLSCHAFT (DE) 2010-05-27 US disclosed
WO-2010055050-A1 RADIATION CURABLE COATING MATERIALS BASF SE (DE) 2010-05-20 WO disclosed
EP-1498281-B1 Printing method using printing plate KONICA MINOLTA MED & GRAPHIC (JP) 2008-12-03 EP disclosed
US-6486225-B1 Photocurable composition SHOWA DENKO KABUSHIKI KAISHA (JP) 2002-11-26 US disclosed
US-6211260-B1 MARKING ROADS WITH CURABLE PAINT, FILLERS, GLASS BEADS, CATIONIC DYES AND QUATERNARY ORGANIC BORATES SHOWA DENKO K.K. (JP) 2001-04-03 US disclosed
US-6110987-A CURED PRODUCTS HAVING AN EXCELLENT APPEARANCE WITHOUT COLORING CAUSED BY POLYMERIZATION INITIATOR SHOWA DENKO K.K. (JP) 2000-08-29 US disclosed
EP-1002817-A2 Photocurable composition SHOWA DENKO KABUSHIKI KAISHA (JP) 2000-05-24 EP disclosed
EP-0915136-A1 Photocurable paint composition for road markings SHOWA DENKO KABUSHIKI KAISHA (JP) 1999-05-12 EP disclosed
US-4942107-A Image-forming material and image recording method using the same FUJI PHOTO FILM CO., LTD. (JP) 1990-07-17 US disclosed
US-4794069-A Spirobenzanthracene phthalide compounds, processes for preparing same and color forming recording materials containing said compounds SHIN NISSO KAKO CO., LTD. (JP) 1988-12-27 US disclosed
US-4251619-A Process for forming photo-polymeric image KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-02-17 US disclosed
US-4111692-A ALIPHATIC NITROGEN COMPOUND, HALOGEN COMPOUND AS FREE RADICAL GENERATOR TOYO BOSEKI KABUSHIKI KAISHA (JP) 1978-09-05 US disclosed
US-4042388-A FREE RADICAL FORMERS, DYES CANON KABUSHIKI KAISHA (JA) 1977-08-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110230617-A1 RADIATION-CURABLE COATING MATERIALS RAD51, MGMT, RAD54L ALDH1A1 2704/4885CYP3A4 3122/4885MAPK1 4399/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.