SCHEMBL753655

SCHEMBL753655

O=S(=O)(c1ccc(Cl)cc1)C(Br)(Br)Br

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.56
CYP3A4 P08684 1/20 0.56
MAPK1 P28482 1/20 0.56
CA1 P00915 4/20 0.52
CA2 P00918 4/20 0.52
CA12 O43570 3/20 0.52
CA3 P07451 3/20 0.52
CA4 P22748 3/20 0.52
CA6 P23280 3/20 0.52
CA5A P35218 3/20 0.52
CA7 P43166 3/20 0.52
CA9 Q16790 3/20 0.52
CA13 Q8N1Q1 3/20 0.52
CA14 Q9ULX7 3/20 0.52
CA5B Q9Y2D0 3/20 0.52
KMT2A Q03164 2/20 0.46
MMP2 P08253 2/20 0.46
MEN1 O00255 1/20 0.46
MMP1 P03956 1/20 0.46
MMP9 P14780 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL750671 1.00 ALDH1A1 (0.56) ALDH1A1CYP3A4MAPK1CA1CA2
SCHEMBL14354527 0.87 ALDH1A1 (0.50) ALDH1A1CYP3A4MAPK1CA1CA2
SCHEMBL2323918 0.80 ALDH1A1 (0.56) ALDH1A1CYP3A4MAPK1CA1CA2
SCHEMBL1828426 0.78 ALDH1A1 (0.54) ALDH1A1CYP3A4MAPK1CA1CA2
SCHEMBL10083746 0.78 ALDH1A1 (0.61) ALDH1A1CYP3A4MAPK1CA1CA2
SCHEMBL5403737 0.77 CA2 (0.54) ALDH1A1MAPK1CA1CA2CA12
SCHEMBL20572271 0.76 ALDH1A1 (0.52) ALDH1A1CYP3A4MAPK1CA1CA2
SCHEMBL2721589 0.75 LMNA (0.54) ALDH1A1CYP3A4CA1CA2CA12
SCHEMBL752983 0.75 GAA (0.56) ALDH1A1CYP3A4CA1CA2CA12
SCHEMBL753683 0.75 GAA (0.56) ALDH1A1CYP3A4CA1CA2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2213166-B1 Biocidal compounds containing 2-methylisothiazolin-3-one and a haloalkylsulfone THOR GMBH (DE) 2012-03-21 EP claimed
EP-2213166-A1 Biocidal compounds containing 2-methylisothiazolin-3-one and a haloalkylsulfone THOR GmbH (DE) 2010-08-04 EP claimed
EP-0137228-B1 PHOTOPOLYMERIZABLE COMPOSITION FUJI PHOTO FILM CO., LTD. (JP) 1988-10-05 EP claimed
EP-2216372-B1 Compounds for preventing Ghost odour THOR GMBH (DE) 2014-06-04 EP disclosed
EP-2213166-B1 Biocidal compounds containing 2-methylisothiazolin-3-one and a haloalkylsulfone THOR GMBH (DE) 2012-03-21 EP disclosed
EP-2216372-A1 Compounds for preventing Ghost odour THOR GmbH (DE) 2010-08-11 EP disclosed
EP-2213166-A1 Biocidal compounds containing 2-methylisothiazolin-3-one and a haloalkylsulfone THOR GmbH (DE) 2010-08-04 EP disclosed