Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.44 |
| ▸ | MGLL | Q99685 | 5/20 | 0.42 |
| ▸ | LTC4S | Q16873 | 2/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL234666 | 0.88 | NR4A1 (0.58) | NR4A1AKR1C3AKR1C2SRD5A2MEN1 | |
| SCHEMBL2743147 | 0.74 | LTC4S (0.56) | NR4A1AKR1C3AKR1C2LTC4S | |
| (4-Chlorophenyl)(Cyclopropyl)Methanone SCHEMBL6220062 | 0.73 | MGLL (0.64) | MGLLMEN1KMT2ALMNAMAPT | |
| (4-Chlorophenyl)(Cyclopropyl)Methanone SCHEMBL392801 | 0.73 | MGLL (0.68) | MGLLMEN1KMT2ALMNAMAPT | |
| SCHEMBL230143 | 0.72 | ALDH1A1 (0.51) | LTC4SPOLBMAPT | |
| SCHEMBL894802 | 0.70 | MGLL (0.60) | MGLLMEN1KMT2ALMNAMAPT | |
| SCHEMBL894800 | 0.70 | MGLL (0.60) | MGLLMEN1KMT2ALMNAMAPT | |
| SCHEMBL4294255 | 0.70 | NR4A1 (0.69) | NR4A1SRD5A2MEN1KMT2APOLB | |
| SCHEMBL231538 | 0.69 | ABL1 (0.49) | AKR1C3AKR1C2MEN1KMT2ALMNA | |
| SCHEMBL23252097 | 0.69 | SRD5A2 (0.59) | NR4A1AKR1C3LTC4SSRD5A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120004228-A1 | Bis Aromatic Compounds for Use as LTC4 Synthase Inhibitors | BIOLIPOX AB (SW) | 2012-01-05 | — | — | US | disclosed |
| US-20120004228-A1 | Bis Aromatic Compounds for Use as LTC4 Synthase Inhibitors | BIOLIPOX AB (SW) | 2012-01-05 | — | — | US | disclosed |
| US-20120004228-A1 | Bis Aromatic Compounds for Use as LTC4 Synthase Inhibitors | BIOLIPOX AB (SW) | 2012-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004228-A1 | Bis Aromatic Compounds for Use as LTC4 Synthase Inhibitors | LTC4S, LTB4R2, LTB4R | NR4A1 2147/4885AKR1C3 77/4885AKR1C2 281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.