Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 6/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PDE9A | O76083 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2318036 | 0.89 | HTT (0.35) | NPBWR1HTTSMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL2324074 | 0.88 | MAPK14 (0.39) | NPBWR1HTTSMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL2321817 | 0.84 | MAPK14 (0.36) | NPBWR1HTTSMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL15565769 | 0.83 | BPTF (0.46) | NPBWR1MCHR1HTTSMN1; SMN2RAB9A | |
| SCHEMBL18672225 | 0.82 | HTT (0.37) | NPBWR1HTTSMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL2360721 | 0.82 | HTT (0.33) | NPBWR1MCHR1HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL14760853 | 0.78 | SMN1; SMN2 (0.48) | NPBWR1MCHR1HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL10616008 | 0.77 | BRD4 (0.43) | NPBWR1MCHR1HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9237268 | 0.76 | RAB9A (0.44) | HTTSMN1; SMN2ALDH1A1RAB9ANPC1 | |
| SCHEMBL9377866 | 0.75 | ALDH1A1 (0.39) | NPBWR1HTTSMN1; SMN2ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2534136-A2 | METHODS AND APPARATUS FOR SYNTHESIZING IMAGING AGENTS, AND INTERMEDIATES THEREOF | Lantheus Medical Imaging, Inc. (US) | 2012-12-19 | — | — | EP | disclosed |
| WO-2011097649-A2 | METHODS AND APPARATUS FOR SYNTHESIZING IMAGING AGENTS, AND INTERMEDIATES THEREOF | LANTHEUS MEDICAL IMAGING, INC. (US) | 2011-08-11 | — | — | WO | disclosed |