SCHEMBL692769

SCHEMBL692769

C=C(C)C(=O)OCCC(CBr)OP(=O)(O)O

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.40
TSHR P16473 3/20 0.39
ALDH1A1 P00352 1/20 0.35
POLB P06746 1/20 0.31
APEX1 P27695 1/20 0.31
HTT P42858 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28127563 0.85 THRB (0.40) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL176508 0.82 THRB (0.38) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL541607 0.81 THRB (0.37) THRBTSHRALDH1A1APEX1
SCHEMBL5173693 0.81 TSHR (0.54) THRBTSHR
SCHEMBL541534 0.80 THRB (0.40) THRBTSHRALDH1A1
SCHEMBL5174125 0.80 TSHR (0.56) THRBTSHR
SCHEMBL5172999 0.80 TSHR (0.56) THRBTSHR
SCHEMBL2324344 0.80 THRB (0.36) THRBTSHRALDH1A1
SCHEMBL5173564 0.80 TSHR (0.56) THRBTSHR
SCHEMBL3652753 0.79 THRB (0.39) THRBTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6984673-B2 Dental cement composition KURARAY CO., LTD. (JP) 2006-01-10 US claimed
EP-3848418-B1 DENTAL CURABLE COMPOSITION AND METHOD FOR PRODUCING DENTAL CURABLE COMPOSITION TOKUYAMA DENTAL CORP (JP) 2024-05-22 EP disclosed
EP-4364718-A1 DENTAL CURABLE COMPOSITION Kuraray Noritake Dental Inc. (JP) 2024-05-08 EP disclosed
EP-2979679-B1 CURABLE COMPOSITION FOR DENTAL USE KURARAY NORITAKE DENTAL INC (JP) 2023-11-29 EP disclosed
CN-111481469-B copolymer 宝丽化学工业有限公司 2023-09-19 CN disclosed
CN-111358713-B copolymer 宝丽化学工业有限公司 2023-09-19 CN disclosed
US-20230255857-A1 DENTAL COMPOSITION CONTAINING ION SUSTAINED-RELEASE GLASS SHOFU INC. (JP) 2023-08-17 US disclosed
US-11648184-B2 Dental composition containing ion sustained-release glass SHOFU INC. (JP) 2023-05-16 US disclosed
CN-111329788-B Copolymer 宝丽化学工业有限公司 2023-03-31 CN disclosed
CN-111329787-B Copolymer 宝丽化学工业有限公司 2023-03-31 CN disclosed
US-20080177384-A1 Intraocular Lens and Process for Producing the Same HOYA Medical Singapore Pte. Ltd. (SG) 2008-07-24 US disclosed
EP-1854490-A1 INTRAOCULAR LENS AND METHOD OF PRODUCING THE SAME Hoya Corporation (JP) 2007-11-14 EP disclosed
US-6790877-B2 Bonding compositions for dental use KURARAY CO., LTD. (JP) 2004-09-14 US disclosed
US-6706260-B1 COMPRISED OF POLYMER HAVING SUCH AS 2-METHACRYLOYLOXYETHYL PHOSPHORYLCHOLINE UNITS; CLEANING AND NECROTIC TISSUE REMOVAL; NONIRRITATING; ACCELERATING REEPITHELIALIZATION AND GRANULATION NOF CORPORATION (JP) 2004-03-16 US disclosed
EP-0980682-B1 Bonding compositions for dental use KURARAY CO (JP) 2003-11-05 EP disclosed
US-20020035169-A1 Bonding compositions for dental use KURARAY CO., LTD (JP) 2002-03-21 US disclosed
US-6355704-B1 BACTERICIDE PRIMERS; BONDING TO TEETH KURARAY CO., LTD. (JP) 2002-03-12 US disclosed
EP-1095665-A1 WOUND-COVERING PREPARATION, WOUND-COVERING MATERIAL, AND METHOD OF WOUND HEALING NOF CORPORATION (JP) 2001-05-02 EP disclosed
EP-0980682-A1 Bonding compositions for dental use KURARAY CO., LTD. (JP) 2000-02-23 EP disclosed
US-5468475-A Moisture preservation for human skin or hair POLA CHEMICAL INDUSTRIES INC. 1995-11-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020035169-A1 Bonding compositions for dental use PTK2, DEK, POLK THRB 3603/4885TSHR 4726/4885ALDH1A1 2444/4885
US-20230255857-A1 DENTAL COMPOSITION CONTAINING ION SUSTAINED-RELEASE GLASS SLCO2B1, CA2, SLCO2A1 THRB 862/4885TSHR 1261/4885ALDH1A1 3160/4885
US-11648184-B2 Dental composition containing ion sustained-release glass SLCO2B1, CA2, SLCO2A1 THRB 862/4885TSHR 1261/4885ALDH1A1 3160/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.