Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 19/20 | 0.72 |
| ▸ | CTSB | P07858 | 3/20 | 0.65 |
| ▸ | CTSL | P07711 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | EGFR | P00533 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28552740 | 0.89 | CTSC (0.73) | CTSCCTSBCTSLCYP1A2CYP2C19 | |
| SCHEMBL23243740 | 0.88 | EGFR (0.75) | CTSCEGFR | |
| SCHEMBL23243722 | 0.87 | CTSC (0.72) | CTSCCTSBCTSLCYP1A2CYP2C19 | |
| SCHEMBL23243689 | 0.86 | CTSC (0.84) | CTSCCTSBCTSLCYP1A2CYP2C19 | |
| SCHEMBL23243684 | 0.85 | CTSC (0.72) | CTSCCTSBCTSLCYP1A2CYP2C19 | |
| SCHEMBL23293740 | 0.84 | CTSC (0.69) | CTSCCTSBCTSLCYP1A2CYP2C19 | |
| SCHEMBL23243677 | 0.84 | CTSC (0.79) | CTSCCTSBCTSLCYP1A2CYP2C19 | |
| SCHEMBL23243721 | 0.84 | CTSC (1.00) | CTSCCTSBCTSLCYP1A2CYP2C19 | |
| SCHEMBL23243746 | 0.83 | EGFR (0.60) | CTSCCTSBCTSLCYP1A2CYP2C19 | |
| SCHEMBL23243675 | 0.83 | CTSC (0.72) | CTSCCTSBCTSLCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3814324-A1 | CATHEPSIN C INHIBITORS | National Institute Of Biological Sciences, Beijing (CN) | 2021-05-05 | — | — | EP | disclosed |
| US-20210114983-A1 | Cathepsin C inhibitors | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2021-04-22 | — | — | US | disclosed |
| US-20210114983-A1 | Cathepsin C inhibitors | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2021-04-22 | — | — | US | disclosed |
| CN-112601742-A | Cathepsin C inhibitors | 北京生命科学研究所 | 2021-04-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210114983-A1 | Cathepsin C inhibitors | CTSF, CTSE, CTSG | CTSC 9/4885CTSB 5/4885CTSL 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.