Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KLK7 | P49862 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23243768 | 1.00 | HPGD (0.41) | HPGDCYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL23243769 | 1.00 | HPGD (0.41) | HPGDCYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL29445322 | 1.00 | HPGD (0.41) | HPGDCYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL23243762 | 0.79 | SLC6A2 (0.41) | HPGDCYP1A2CYP3A4CYP2D6MEN1 | |
| SCHEMBL29445320 | 0.79 | SLC6A2 (0.41) | HPGDCYP1A2CYP3A4CYP2D6MEN1 | |
| SCHEMBL23243764 | 0.79 | SLC6A2 (0.41) | HPGDCYP1A2CYP3A4CYP2D6MEN1 | |
| SCHEMBL23243763 | 0.79 | SLC6A2 (0.41) | HPGDCYP1A2CYP3A4CYP2D6MEN1 | |
| SCHEMBL25325127 | 0.76 | ALOX5 (0.31) | L3MBTL1 | |
| SCHEMBL25326895 | 0.76 | ALOX5 (0.31) | L3MBTL1 | |
| SCHEMBL25912810 | 0.76 | ALOX5 (0.31) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210114977-A1 | AN IMPROVED ASYMMETRIC SYNTHESIS OF alpha-BRANCHED CHIRAL AMINES | Piramal Enterprises Limited (IN) | 2021-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210114977-A1 | AN IMPROVED ASYMMETRIC SYNTHESIS OF alpha-BRANCHED CHIRAL AMINES | SLC6A12, BCAT2, BET1 | HPGD 4383/4885CYP1A2 774/4885CYP3A4 1071/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.