Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | NOS1 | P29475 | 1/20 | 0.51 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.46 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27914458 | 0.90 | HRH3 (0.59) | NCF1HRH3ALDH1A1HTTKDM4E | |
| SCHEMBL13834647 | 0.84 | NCF1 (0.60) | NCF1HRH3ALDH1A1HTTKDM4E | |
| SCHEMBL29809064 | 0.84 | NCF1 (0.60) | NCF1HRH3ALDH1A1HTTKDM4E | |
| SCHEMBL578569 | 0.84 | NCF1 (0.60) | NCF1HRH3ALDH1A1HTTKDM4E | |
| SCHEMBL11196105 | 0.83 | NCF1 (0.83) | NCF1HRH3ALDH1A1HTTKDM4E | |
| SCHEMBL3839191 | 0.81 | HRH3 (0.60) | NCF1HRH3NPC1TP53RAB9A | |
| SCHEMBL2324448 | 0.81 | SIGMAR1 (0.57) | HRH3CXCR4MEN1KMT2A | |
| Bromide SCHEMBL27780447 | 0.81 | NCF1 (0.64) | NCF1HRH3ALDH1A1HTTKDM4E | |
| SCHEMBL2360324 | 0.80 | HRH3 (0.65) | HRH3ALDH1A1HPGDNOS1SMN1; SMN2 | |
| SCHEMBL22711383 | 0.79 | NCF1 (0.71) | NCF1HRH3ALDH1A1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050222098-A1 | Regulation of meiosis | NOVO NORDISK A/S (DK) | 2005-10-06 | — | — | US | disclosed |
| EP-0767798-B1 | STEROL DERIVATIVES USED FOR REGULATION OF MEIOSIS | NOVO NORDISK AS (DK) | 2003-09-03 | — | — | EP | disclosed |
| US-20030004148-A1 | Regulation of meiosis | NOVO NORDISK A/S (DK) | 2003-01-02 | — | — | US | disclosed |
| CN-1341590-A | Proteinase inhibitor | SMITHKLINE BEECHEM CORP (US) | 2002-03-27 | — | — | CN | disclosed |
| CN-1341592-A | Proteinase inhibitor | SMITHKLINE BEECHEM CORP (US) | 2002-03-27 | — | — | CN | disclosed |
| CN-1341593-A | Proteinase inhibitor | SMITHKLINE BEECHEM CORP (US) | 2002-03-27 | — | — | CN | disclosed |
| CN-1068333-C | Sterol derivatives used for regulation of meiosis | NOVO NORDISK AS (DK) | 2001-07-11 | — | — | CN | disclosed |
| CN-1151164-A | Sterol derivatives used for regulation of meiosis | NOVO NORDISK AS (DK) | 1997-06-04 | — | — | CN | disclosed |
| EP-0767798-A1 | STEROL DERIVATIVES USED FOR REGULATION OF MEIOSIS | NOVO NORDISK A/S (DK) | 1997-04-16 | — | — | EP | disclosed |
| WO-1996000235-A1 | STEROL DERIVATIVES USED FOR REGULATION OF MEIOSIS | NOVO NORDISK A/S (DK) | 1996-01-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222098-A1 | Regulation of meiosis | ALPG, MNS1, BUB1B | NCF1 1867/4885HRH3 3595/4885ALDH1A1 2659/4885 |
| US-20030004148-A1 | Regulation of meiosis | ALPG, MNS1, BUB1B | NCF1 1867/4885HRH3 3595/4885ALDH1A1 2659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.