Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.40 |
| ▸ | ABAT | P80404 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | ALDH1A3 | P47895 | 3/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3857336 | 0.87 | ALDH1A1 (0.43) | ALDH1A1TSHRTRIM24HPGDALDH5A1 | |
| SCHEMBL36740 | 0.87 | ALDH1A1 (0.50) | ALDH1A1TSHRTRIM24HPGDALDH5A1 | |
| SCHEMBL30360260 | 0.87 | ALDH1A1 (0.50) | ALDH1A1TSHRTRIM24HPGDALDH5A1 | |
| SCHEMBL29234008 | 0.84 | ALDH1A1 (0.43) | ALDH1A1TSHRTRIM24HPGDALDH5A1 | |
| SCHEMBL14045435 | 0.83 | ALDH1A1 (0.58) | ALDH1A1TSHRTRIM24HPGDALDH5A1 | |
| SCHEMBL30504088 | 0.83 | ALDH1A1 (0.64) | ALDH1A1TSHRTRIM24HPGDALDH5A1 | |
| SCHEMBL22428 | 0.83 | ALDH1A1 (0.64) | ALDH1A1TSHRTRIM24HPGDALDH5A1 | |
| SCHEMBL4493705 | 0.83 | ALDH1A1 (0.46) | ALDH1A1TSHRTRIM24HPGDALDH5A1 | |
| SCHEMBL498989 | 0.83 | ALDH1A1 (0.64) | ALDH1A1TSHRTRIM24HPGDALDH5A1 | |
| SCHEMBL3116390 | 0.81 | ALDH1A1 (0.43) | ALDH1A1TSHRTRIM24HPGDALDH5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2609089-A1 | SELECTIVE 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITORS | Universität des Saarlandes (DE) | 2013-07-03 | — | — | EP | disclosed |
| WO-2012025638-A1 | SELECTIVE 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITORS | Universität des Saarlandes (DE) | 2012-03-01 | — | — | WO | disclosed |
| WO-2012025638-A1 | SELECTIVE 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITORS | Universität des Saarlandes (DE) | 2012-03-01 | — | — | WO | disclosed |
| EP-1206429-A2 | STILBENES WITH VASCULAR DAMAGING ACTIVITY | Angiogene Pharmaceuticals Ltd (GB) | 2002-05-22 | — | — | EP | disclosed |
| WO-2001012579-A2 | NEW STILBENES WITH VASCULAR DAMAGING ACTIVITY | ANGIOGENE PHARMACEUTICALS LTD. (GB) | 2001-02-22 | — | — | WO | disclosed |