Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | FDPS | P14324 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.50 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.50 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.50 |
| ▸ | ABAT | P80404 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30504088 | 1.00 | ALDH1A1 (0.64) | ALDH1A1TSHRFDPSHPGDAOX1 | |
| SCHEMBL22428 | 0.94 | ALDH1A1 (0.64) | ALDH1A1TSHRFDPSHPGDAOX1 | |
| SCHEMBL30360260 | 0.92 | ALDH1A1 (0.50) | ALDH1A1TSHRFDPSHPGDAOX1 | |
| SCHEMBL36740 | 0.92 | ALDH1A1 (0.50) | ALDH1A1TSHRFDPSHPGDAOX1 | |
| SCHEMBL9707833 | 0.85 | ALDH1A1 (0.57) | ALDH1A1TSHRFDPSHPGDAOX1 | |
| SCHEMBL25365134 | 0.84 | TRPA1 (0.50) | ALDH1A1TSHRHPGDTDP1TTR | |
| SCHEMBL9707829 | 0.83 | ALDH1A1 (0.54) | ALDH1A1TSHRFDPSHPGDAOX1 | |
| SCHEMBL3116390 | 0.83 | ALDH1A1 (0.43) | ALDH1A1TSHRFDPSHPGDAOX1 | |
| SCHEMBL3857336 | 0.83 | ALDH1A1 (0.43) | ALDH1A1TSHRFDPSHPGDAOX1 | |
| SCHEMBL29234008 | 0.83 | ALDH1A1 (0.43) | ALDH1A1TSHRFDPSHPGDAOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6943194-B1 | Synthesis of phenstatin and prodrugs thereof | ARIZONA BOARD OF REGENTS, ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2005-09-13 | — | — | US | claimed |
| EP-1045689-A4 | SYNTHESIS OF PHENSTATIN AND PRODRUGS THEREOF | UNIV ARIZONA STATE (US) | 2003-04-23 | — | — | EP | claimed |
| JP-2002500184-A | — | — | 2002-01-08 | — | — | JP | claimed |
| EP-1045689-A1 | SYNTHESIS OF PHENSTATIN AND PRODRUGS THEREOF | ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA acting for and on behalf of ARIZONA STATE UNIVERSITY (US) | 2000-10-25 | — | — | EP | claimed |
| WO-1999034788-A1 | SYNTHESIS OF PHENSTATIN AND PRODRUGS THEREOF | ARIZONA BOARD OF REGENTS, A BODY CORPORATE, ACTING ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 1999-07-15 | — | — | WO | claimed |
| EP-4676937-A1 | METHODS OF SYNTHESIZING FLUORINATED MACROCYCLES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2026-01-14 | — | — | EP | disclosed |
| WO-2024191821-A1 | METHODS OF SYNTHESIZING FLUORINATED MACROCYCLES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-09-19 | — | — | WO | disclosed |
| CN-116535304-A | Erianin analogue, and synthetic method and application thereof | 中国科学院成都生物研究所 | 2023-08-04 | — | — | CN | disclosed |
| US-20220251039-A1 | Diaryl-B-Lactam Compound and Preparation Method and Pharmaceutical Use Thereof | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2022-08-11 | — | — | US | disclosed |
| EP-3438105-B1 | DIARYL- -LACTAM COMPOUND AND PREPARATION METHOD AND PHARMACEUTICAL USE THEREOF | UNIV FUDAN (CN) | 2022-01-05 | — | — | EP | disclosed |
| EP-3438105-B1 | DIARYL- -LACTAM COMPOUND AND PREPARATION METHOD AND PHARMACEUTICAL USE THEREOF | UNIV FUDAN (CN) | 2022-01-05 | — | — | EP | disclosed |
| CN-107235883-B | Diaryl-beta-lactam compound, preparation method thereof and application thereof in pharmacy | 复旦大学 | 2021-06-29 | — | — | CN | disclosed |
| WO-2004099139-A1 | INDOLE-CONTAINING COMPOUNDS WITH ANTI-TUBULIN AND VASCULAR TARGETING ACTIVITY | BAYLOR UNIVERSITY (US) | 2004-11-18 | — | — | WO | disclosed |
| EP-1461311-A2 | UREA DERIVATIVES AS VR1-ANTAGONISTS | Bayer HealthCare AG (DE) | 2004-09-29 | — | — | EP | disclosed |
| US-20040143023-A1 | Materials and methods for synthesizing stilbenes | HADFIELD JOHN ANTHONY (GB) | 2004-07-22 | — | — | US | disclosed |
| US-6593374-B2 | Such as 3-(3'4'5'-trimethoxybenzoyl)-2-(3'benzylphosphate 4'methoxyphenyl)-6-methoxybenzo(b)thiophene; functionalized to prepare phosphate esters, phosphate salts, and phosphoramidates useful as antitumor agents | BAYLOR UNIVERSITY | 2003-07-15 | — | — | US | disclosed |
| WO-2003055848-A2 | UREA DERIVATIVES AS VR1- ANTAGONISTS | BAYER HEALTHCARE AG (DE) | 2003-07-10 | — | — | WO | disclosed |
| EP-1263763-A2 | TUBULIN BINDING LIGANDS AND CORRESPONDING PRODRUG CONSTRUCTS | BAYLOR UNIVERSITY (US) | 2002-12-11 | — | — | EP | disclosed |
| US-20020055643-A1 | Tubulin binding ligands and corresponding prodrug constructs | MATEON THERAPEUTICS, INC. | 2002-05-09 | — | — | US | disclosed |
| WO-2001068654-A2 | TUBULIN BINDING LIGANDS AND CORRESPONDING PRODRUG CONSTRUCTS | BAYLOR UNIVERSITY (US) | 2001-09-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020055643-A1 | Tubulin binding ligands and corresponding prodrug constructs | TUBB, TUBB3, TUBB4A | ALDH1A1 3462/4885TSHR 2797/4885FDPS 606/4885 |
| US-20220251039-A1 | Diaryl-B-Lactam Compound and Preparation Method and Pharmaceutical Use Thereof | PEPD, SQLE, BACE1 | ALDH1A1 1396/4885TSHR 4847/4885FDPS 21/4885 |
| US-20040143023-A1 | Materials and methods for synthesizing stilbenes | DPP4, COASY, ACSL4 | ALDH1A1 1344/4885TSHR 1493/4885FDPS 174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.